Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65? Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

September 20, 2013: Notice of Intent to Change the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: Dichloroacetic Acid

Intent to change the basis for the listing of dichloroacetic acid as known to the state to cause reproductive toxicity under the Safe Drinking Water and Toxic Enforcement Act of 1986. Dichloroacetic acid was listed based on its identification as causing male reproductive toxicity in the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLVs). The proposed new mechanism for listing is via the authoritative bodies mechanism.

September 20, 2013: Comment Period - Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead

Comment Period on the Notice of Intent to change the basis for the listing of 1,2-dibromo-3-chloropropane (DBCP), ethylene oxide and lead as known to the state to cause reproductive toxicity

September 20, 2013: Hazard Identification Materials to Support Reconsideration of Listing: 9 Chemicals Listed Via the Labor Code as Known to the State of California to Cause Reproductive Toxicity

Hazard identification document to support the reconsideration of 9 chemicals listed under Proposition 65 as known to cause reproductive toxicity. Chemicals to be discussed at the November 21, 2013 DART meeting.

September 20, 2013: Comment Period - Notice of Intent to Change the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: Dichloroacetic Acid

Comment Period - Notice of Intent to Change the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: Dichloroacetic Acid

September 20, 2013: Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead

Intent to change the basis for the listing of 1,2-dibromo-3-chloropropane (DBCP), ethylene oxide and lead as known to the state to cause reproductive toxicity. The original listing based on Labor Code is replaced with listing via the formally required to be labeled or identified mechanism.