Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65? Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

October 23, 2014: Comment Period - Request for Relevant Information on the Carcinogenic Hazards of Diaminotoluenes

Comment Period on the Request for Relevant Information on the Carcinogenic Hazards of Diaminotoluenes

October 23, 2014: Request for Relevant Information on the Carcinogenic Hazards of Diaminotoluenes

OEHHA received a petition from Big Lots Stores, Inc. for reconsideration of listing for diaminotoluene (mixed) on October 21, 2014. The CIC will consider the available scientific evidence on the chemical group diaminotoluene and individual isomers and decide whether diaminotoluenes as a group, the mixtures or any individual isomers should be listed under Proposition 65

September 16, 2014: Request for Public Participation on Potential Regulatory Actions

Solicitation of input and information on possible regulatory actions and the priority level for each potential action. OEHHA is planning to schedule a workshop to discuss the next steps in its regulatory reform/update projects.

September 16, 2014: Comment Period - Request for Public Participation on Potential Regulatory Actions

Comment Period on the request for public participation on potential regulatory actions and the priority level for each potential action

September 12, 2014: 2nd Modification to Text of Proposed Section 25904 Listings by Reference to the California Labor Code

Additional changes to the proposed regulation and Initial Statement of Reasons to add section 25904 to Title 27 of the California Code of Regulations. Subsection (e) amended to remove the language which stated that once a chemical no longer meets the requirements for listing, the chemical would remain on the list pending committee review.