Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65?  Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

Release of Final Interpretive Guideline No. 2012-001, Consumption of Methanol Resulting from Pectin that Occurs Naturally In Fruits And Vegetables

Proposal to establish a Maximum Allowable Dose Levels for methanol of 47,000 micrograms per day for inhalation and 23,000 micrograms per day for ingestion.  Concurrently, an interpretive guideline for methanol resulting from pectin that occurs naturally in fruits and vegetables is being published.

OEHHA proposal to update the existing regulatory levels posing no significant risk for trichloroethylene, to 14 micrograms per day for oral exposure and 50 micrograms per day for inhalation exposure.

4-Methylimidazole (4-MEI) was listed under Proposition 65 list because the National Toxicology Program found 4­MEI caused lung tumors in laboratory animals.

Extension of comment period on the notice of intent to ist benzophenone, coconut oil diethanolamine condensate (cocamide diethanolamine), diethanolamine and 2-methylimidazole as known to the state to cause cancer.