Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Safe harbor levels, which include No Significant Risk Levels (NSRLs) for cancer-causing chemicals and Maximum Allowable Dose Levels (MADLs) for chemicals causing reproductive toxicity, have been established for many of the chemicals listed under Proposition 65. Exposure levels and discharges to drinking water sources that are below the safe harbor levels are exempt from the requirements of Proposition 65. In some instances, enforcement actions may have resulted in negotiated exposure levels relative to specific settlement agreements. Please visit the Attorney General's Proposition 65 web site at https://oag.ca.gov/prop65 for further information about specific enforcement actions.

Below is a list of NSRLs and MADLs established in regulation in Title 27, Cal. Code of Regulations, Sections 25705, 25709 and 25805. These safe harbor levels do not preclude the use of alternative levels that can be demonstrated by their users as being scientifically valid. A hyperlink is provided for those NSRLs or MADLs for which the documentation of their derivation is electronically available.

OEHHA has also prioritized certain chemicals for NSRL development.

You can download the entire list of NSRLs and MADLs as an excel file using the export button below.

Safe Harbor List

Note:Opening this file will require you to click “yes” to continue.

Sort Name Chemical NSRL (μg/day)ª MADL (μg/day)ª
Acetaldehyde Acetaldehyde 90 (inhalation)
Acetamide Acetamide 10
Acrylamide Acrylamide 0.2 140
Acrylonitrile Acrylonitrile 0.7
Actinomycin D Actinomycin D 0.00008
Aldrin Aldrin 0.04
Amino-2-methylanthraquinone 1-Amino-2-methylanthraquinone 5
Amino-4-(isopropyl-d7-amino)-6-chloro-triazine Des-ethyl atrazine (DEA) 100 (oral)
Amino-9-ethylcarbazolehydrochloride 3-Amino-9-ethylcarbazole hydrochloride 9
Amino-alpha-carboline A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 2
Aminoanthraquinone 2-Aminoanthraquinone 20
Aminoazotoluene o-Aminoazotoluene 0.2
Aminobiphenyl 4-Aminobiphenyl (4-aminodiphenyl) 0.03
Amitrole Amitrole 0.7
Aniline Aniline 100
Anisidine o-Anisidine 5
Anisidine Hydrochloride o-Anisidine Hydrochloride 7
Antimony Trioxide Antimony Oxide (Antimony trioxide) 0.13 (inhalation)
Aramite Aramite 20
Arsenic Arsenic (inorganic arsenic compounds) 0.06 (inhalation)
10 (except inhalation)
Asbestos Asbestos 100 fibers inhaled/day ᵈ
Atrazine Atrazine 100 (oral)
Atrazine-desisopropyl Des-isopropyl atrazine (DIA) 100 (oral)
Auramine Auramine 0.8
Avermectin B1 (Abamectin) Avermectin B1 (Abamectin) 4.4
Azaserine Azaserine 0.06
Azathioprine Azathioprine 0.4
Azobenzene Azobenzene 6
Benzene Benzene 6.4 (oral)
13 (inhalation) 		24 (oral)
49 (inhalation)
Benzidine Benzidine (and its salts) 0.001
Benzofuran Benzofuran 1.1
Benzo[a]pyrene Benzo[a]pyrene 0.06
Benzo[b]fluoranthene Benzo[b]fluoranthene 0.096
Benzo[j]fluoranthene Benzo[j]fluoranthene 0.11 (oral)
Benzyl Chloride Benzyl Chloride 4
Benzyl Violet 4B Benzyl Violet 4B 30
Benz[a]anthracene Benz[a]anthracene 0.033 (oral)
Beryllium Beryllium and beryllium compounds 0.1 (Beryllium)
0.1 (Beryllium oxide)
0.0002 (Beryllium sulfate)
Bis(2-chloroethyl) Ether Bis(2-chloroethyl) Ether 0.3
Bis(2-chloromethyl) Ether Bis(chloromethyl) Ether 0.02
Bisphenol-A Bisphenol A (BPA) 3 (dermal exposure from solid materials)
Bromochloroacetic Acid Bromochloroacetic Acid 0.7
Bromodichloroacetic acid Bromodichloroacetic acid 0.95
Bromodichloromethane Bromodichloromethane 5
Bromoethane Bromoethane 96
Bromoform Bromoform 64
Butadiene 1,3-Butadiene 0.4
Butyl Benzyl Phthalate Butyl Benzyl Phthalate 1200 (oral)
Butylated Hydroxyanisole Butylated Hydroxyanisole 4000
Butyric Acid 2,4-D Butyric Acid 910
Butyrolactone beta-Butyrolactone 0.7
C.I. Basic Red 9 Monohydrochloride C.I. Basic Red 9 Monohydrochloride 3
C.I. Direct Blue 218 C.I. Direct Blue 218 50
Cadmium Cadmium 0.05 (inhalation) 4.1 (oral)
Captafol Captafol 5
Captan Captan 300
Carbazole Carbazole 4.1
Carbon Tetrachloride Carbon Tetrachloride 5
Carboxymethyl-n-Nitrosourea N-Carboxymethyl-N-Nitrosourea 0.70
Chlorambucil Chlorambucil 0.002
Chlordane Chlordane 0.5
Chlordecone Chlordecone (Kepone) 0.04
Chlorendic Acid Chlorendic Acid 8
Chlorinated paraffins (Avg. chain length C12; approx. 60 percent chlorine by weight) Chlorinated Paraffins (Avg. chain length C12; approx. 60 percent chlorine by weight) 8
Chloro-2-methylpropene 3-Chloro-2-methylpropene 5
Chloro-4,6-diamino-1,3,5-triazine 2,4‑diamino‑6‑chloro-s-triazine (DACT) 100 (oral)
Chloro-o-toluidine p-Chloro-o-toluidine 3
Chloro-o-toluidine, strong acid salts of p-Chloro-o-toluidine, strong acid salts of 3.3 (p-Chloro-o-toluidine, hydrochloride)
Chloro-ortho-phenylenediamine 4-Chloro-o-phenylenediamine 40
Chloro-α,α,α-trifluorotoluene (para-Chlorobenzo trifluoride, PCBTF) p-Chloro-α,α,α-trifluorotoluene (para-Chlorobenzo trifluoride, PCBTF) 23
Chloroaniline p-Chloroaniline 1.5
Chloroaniline Hydrochloride p-Chloroaniline Hydrochloride 1.9
Chloroethane (Ethyl Chloride) Chloroethane (Ethyl Chloride) 150
Chloroform Chloroform 20 (oral)
40 (inhalation)
Chloromethyl Methyl Ether (Technical Grade) Chloromethyl Methyl Ether (Technical Grade) 0.3
Chlorothalonil Chlorothalonil 41
Chlorozotocin Chlorozotocin 0.003
Chlorpyrifos Chlorpyrifos 0.58 (oral/inhalation)
7.2 (dermal)
Chromium-hexavalent Chromium (hexavalent compounds) 0.001 (inhalation) 8.2 (oral)
Chrysene Chrysene 0.35 (oral)
Cinnamyl Anthranilate Cinnamyl Anthranilate 200
Coke Oven Emissions Coke Oven Emissions 0.3
Cresidine p-Cresidine 5
Cupferron Cupferron 3
Cyanide Hydrogen cyanide (HCN) and cyanide salts (CN salts) 10 (oral) (Hydrogen cyanide)
9.8 (oral) (Cyanide salts that readily dissociate in solution (expressed as cyanide))
25 (oral) (Potassium cyanide)
19 (oral) (Sodium cyanide)
Cyclophosphamide (Anhydrous) Cyclophosphamide (Anhydrous) 1
Cyclophosphamide (Hydrated) Cyclophosphamide (Hydrated) 1
D&C Red No. 9 D&C Red No. 9 100
Dacarbazine Dacarbazine 0.01
Daminozide Daminozide 40
Dantron Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) 9
DDT, DDD, DDE (combination) DDT, DDD, DDE (combination) 2
Di(2-ethylhexyl)phthalate Di(2-ethylhexyl)phthalate (DEHP) 310 4200 (intravenous) (Adult) ᵇ
600 (intravenous) (Infant boys, age 29 days - 24 mos.) ᵇ
210 (intravenous) (Neonatal infant boys, age 0 - 28 days) ᵇ
410 (oral) (Adult) ᵇ
58 (oral) (Infant boys, age 29 days - 24 mos.) ᵇ
20 (oral) (Neonatal infant boys, age 0 - 28 days) ᵇ
Di-isodecyl Phthalate (DIDP) Di-isodecyl Phthalate (DIDP) 2200
Di-n-butyl Phthalate Di-n-butyl Phthalate (DBP) 8.7
Di-n-hexyl Phthalate (DnHP) Di-n-hexyl Phthalate (DnHP) 2200 (oral)
Diaminoanisole 2,4-Diaminoanisole 30
Diaminoanisole Sulfate 2,4-Diaminoanisole Sulfate 50
Diaminodiphenyl Ether 4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) 5
Diaminotoluene 2,4-Diaminotoluene 0.2
Dianisidine 3,3'-Dimethoxybenzidine (o-Dianisidine) 0.15
Dibenzo[a,h]pyrene Dibenzo[a,h]pyrene 0.0054 (oral)
Dibenzo[a,i]pyrene Dibenzo[a,i]pyrene 0.0050 (oral)
dibenzo[c,g]carbazole 7H-dibenzo[c,g]carbazole 0.0030 (oral)
Dibenz[a,h]anthracene Dibenz[a,h]anthracene 0.2
Dibromo-3-chloropropane 1,2-Dibromo-3-chloropropane (DBCP) 0.1 3.1 (oral)
4.3 (inhalation)
Dibromoacetic Acid Dibromoacetic Acid 2.8
Dibromoethane Ethylene dibromide 0.2 (oral)
3 (inhalation)
Dichloroacetic Acid Dichloroacetic Acid 17
Dichlorobenzene p-Dichlorobenzene 20
Dichlorobenzidine 3,3'-Dichlorobenzidine 0.6
Dichloroethane 1,1-Dichloroethane 100
Dichloroethane Ethylene dichloride (1,2-Dichloroethane) 10
Dichloroethylene Vinylidene Chloride (1,1-Dichloroethylene) 0.88
Dichloropropane 1,2-Dichloropropane 9.7
Dichloropropene 1,3-Dichloropropene 3.7 (oral)
3.7 (inhalation)
Dichlorvos DDVP (Dichlorvos) 2
Dieldrin Dieldrin 0.04
Diethylstilbestrol Diethylstilbestrol (DES) 0.002
Diglycidyl Resorcinol Ether Diglycidyl Resorcinol Ether (DGRE) 0.4
Dihydrosafrole Dihydrosafrole 20
Diisononyl Phthalate Diisononyl Phthalate (DINP) 146
Dimethlybenzidine Dihydrochloride 3,3'-Dimethylbenzidine dihydrochloride 0.059
Dimethoxybenzidine Dihydrochloride 3,3'-Dimethoxybenzidine dihydrochloride 0.19
Dimethylaminoazobenzene 4-Dimethylaminoazobenzene 0.2
Dimethylbenz(a)anthracene 7,12-Dimethylbenz(a)anthracene 0.003
Dimethylbenzidine 3,3'-Dimethylbenzidine (ortho-Tolidine) 0.044
Dimethylcarbamoyl Chloride Dimethylcarbamoyl Chloride 0.05
Dimethylhydrazine 1,2-Dimethylhydrazine 0.001
Dimethylvinylchloride Dimethylvinylchloride 20
Dinitrobenzene m-Dinitrobenzene 38
Dinitrotoluene 2,4-Dinitrotoluene 2
Dioxane 1,4-Dioxane 30
Direct Black 38 (Technical Grade) Direct Black 38 (Technical Grade) 0.09
Direct Blue 6 (Technical Grade) Direct Blue 6 (Technical Grade) 0.09
Direct Brown 95 (Technical Grade) Direct Brown 95 (Technical Grade) 0.1
Disodium Cyanodithioimidocarbonate Disodium Cyanodithioimidocarbonate 56 (oral)
170 (oral) as 32% pesticidal formation
Disperse Blue 1 (Technical Grade) Disperse Blue 1 200
Epichlorohydrin Epichlorohydrin 9
Estradiol 17B Estradiol 17B 0.02
Ethyl Dipropylthiocarbamate Ethyl Dipropylthiocarbamate 700 (oral and inhalation)
6700 (dermal)
Ethyl-4-4'-dichlorobenzilate Ethyl-4-4'-dichlorobenzilate 7
Ethylbenzene Ethylbenzene 54 (inhalation)
41 (oral)
Ethylene Glycol Ethylene glycol (ingested) 8700 (oral)
Ethylene Glycol Monoethyl Ether Ethylene Glycol Monoethyl Ether 750 (oral)
960 (inhalation)
Ethylene Glycol Monoethyl Ether Acetate Ethylene Glycol Monoethyl Ether Acetate 1100 (oral)
1400 (inhalation)
Ethylene Glycol Monomethyl Ether Ethylene Glycol Monomethyl Ether 63 (oral)
Ethylene Glycol Monomethyl Ether Acetate Ethylene Glycol Monomethyl Ether Acetate 98 (oral)
Ethylene Oxide Ethylene Oxide 2 20
Ethylene Thiourea Ethylene Thiourea 20
Ethyleneimine Ethyleneimine 0.01
Folpet Folpet 200
Formaldehyde Formaldehyde (gas) 40
Furaltadone 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone 0.18
Furathiazole N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 0.5
Furidiazine 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 0.04
Furmecyclox Furmecyclox 20
Furylfuramide AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide 3
Glu-P-1 (2-Amino-6-methyldipyrido[1-2-a:3'-2'-d]imidazole) Glu-P-1 (2-Amino-6-methyldipyrido[1-2-a:3'-2'-d]imidazole) 0.1
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) 0.5
Glycidol Glycidol 0.54
Glyphosate Glyphosate 1100
Gyromitrin Gyromitrin 0.07
HC Blue 1 HC Blue 1 10
Heptachlor Heptachlor 0.2
Heptachlor Epoxide Heptachlor Epoxide 0.08
Hexachlorobenzene Hexachlorobenzene 0.4
Hexachlorocyclohexane (Technical Grade) Hexachlorocyclohexane (Technical Grade) 0.2
Hexachlorodibenzo-p-dioxin Hexachlorodibenzodioxin 0.0002
Hexachloroethane Hexachloroethane 20
Hexane n-Hexane 28,000 (oral)
20,000 (inhalation)
Hydramethylnon Hydramethylnon 120 (oral)
Hydrazine Hydrazine 0.04
Hydrazine sulfate Hydrazine sulfate 0.2
Hydrazobenzene Hydrazobenzene (1,2-Diphenylhydrazine) 6
0.8
Imazalil Imazalil 11
IQ (2-Amino-3-methylimidazo-[4-5-f]quinoline) IQ (2-Amino-3-methylimidazo-[4-5-f]quinoline) 0.5
Isobutyl Nitrite Isobutyl Nitrite 7.4
Lasiocarpine Lasiocarpine 0.09
Lead Lead 15 (oral) 0.5
Lead Acetate Lead Acetate 23 (oral)
Lead and Lead Compounds Lead and Lead Compounds 15 (oral) 0.5
Lead Phosphate Lead Phosphate 58 (oral)
Lead Subacetate Lead Subacetate 41 (oral)
Lindane and other hexachlorocyclohexane isomers Lindane and other hexachlorocyclohexane isomers 0.3 Hexachlorocyclohexane (alpha isomer)
0.5 Hexachlorocyclohexane (beta isomer)
0.6 Hexachlorocyclohexane (gamma isomer)
Linuron Linuron 460
Malathion Malathion 180
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2-3-b]indole) Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole) 0.6
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) 0.46
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) 0.41
Melphalan Melphalan 0.005
Metham Sodium Metham Sodium 290
Methanol Methanol 47,000 (inhalation)
23,000 (oral)
Methyl Bromide Methyl Bromide, as a structural fumigant 810 (inhalation)
Methyl Carbamate Methyl Carbamate 160
Methyl Methanesulfonate Methyl Methanesulfonate 7
Methyl-1-nitroanthraquinone (of uncertain purity) 2-Methyl-1-nitroanthraquinone (of uncertain purity) 0.2
Methyl-n-Nitro-n-Nitrosoguanidine N-Methyl-N'-nitro-N-nitrosoguanidine 0.08
Methylcholanthrene 3-Methylcholanthrene 0.03
Methylchrysene 5-Methylchrysene 0.00844 (oral)
Methylene bis(2-chloroaniline) 4,4'-Methylene bis(2-chloroaniline) 0.5
Methylene bis(2-methylaniline) 4,4'-Methylene bis(2-methylaniline) 0.8
Methylene Chloride (Dichloromethane) Dichloromethane (Methylene Chloride) 50
200 (inhalation)
Methylenedianiline 4,4'-Methylenedianiline 0.4
Methylenedianiline Dihydrochloride 4,4'-Methylenedianiline dihydrochloride 0.6
Methylhydrazine Methylhydrazine and its salts 0.058 (oral)
0.090 (inhalation)
0.18 (Methylhydrazine sulfate)
Methylimidazole 4-Methylimidazole 29
Methylpyrrolidone N-Methylpyrrolidone 3200 (inhalation)
17000 (dermal)
Methylthiouracil Methylthiouracil 2
Michlers Ketone Michler's Ketone 0.8
Mirex Mirex 0.04
Mitomycin C Mitomycin C 0.00009
Monocrotaline Monocrotaline 0.07
MX (3-chloro-4-(dichloromethyl)5-hydroxy-2-(5H)-furanone) MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone) 0.11
Nalidixic Acid Nalidixic Acid 28
Naphthalene Naphthalene 5.8
Naphthylamine 2-Naphthylamine 0.4
Nickel Refinery Dust Nickel Refinery Dust from the Pyrometallurgical Process 0.8
Nickel Subsulfide Nickel Subsulfide 0.4
Nifuradene 1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone 0.4
Nifurthiazole 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole 0.3
Nitrilotriacetic Acid Nitrilotriacetic Acid 100
Nitrilotriacetic Acid- Trisodium Salt Monohydrate Nitrilotriacetic Acid, Trisodium Salt Monohydrate 70
Nitroacenaphthene 5-Nitroacenaphthene 6
Nitrofen (Technical Grade) Nitrofen (Technical Grade) 9
Nitrofurazone Nitrofurazone 0.5
Nitromethane Nitromethane 39
Nitroso-n-Ethylurea N-Nitroso-N-ethylurea 0.03
Nitroso-n-methylethylamine N-Nitrosomethylethylamine 0.03
Nitroso-n-Methylurea N-Nitroso-N-methylurea 0.006
Nitroso-n-Methylurethane N-Nitroso-N-methylurethane 0.006
Nitrosodi-n-Butylamine N-Nitrosodi-n-Butylamine 0.06
Nitrosodi-n-Propylamine N-Nitrosodi-n-propylamine 0.1
Nitrosodiethanolamine n-Nitrosodiethanolamine 0.3
Nitrosodiethylamine n-Nitrosodiethylamine 0.02
Nitrosodimethylamine n-Nitrosodimethylamine 0.04
Nitrosodiphenylamine N-Nitrosodiphenylamine 80
Nitrosodiphenylamine p-Nitrosodiphenylamine 30
nitrosomethylamino)-1(3-pyridyl)-1-butanone 4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone 0.014
Nitrosomorpholine n-Nitrosomorpholine 0.1
Nitrosonornicotine N-Nitrosonornicotine 0.5
Nitrosopiperidine N-Nitrosopiperidine 0.07
Nitrosopyrrolidine N-Nitrosopyrrolidine 0.3
Pentachlorophenol Pentachlorophenol 40
Phenacetin Phenacetin 300
Phenazopyridine Phenazopyridine 4
Phenazopyridine Hydrochloride Phenazopyridine Hydrochloride 5
Phenesterin Phenesterin 0.005
Phenobarbital Phenobarbital 2
Phenoxybenzamine Phenoxybenzamine 0.2
Phenoxybenzamine Hydrochloride Phenoxybenzamine Hydrochloride 0.3
Phenyl Glycidyl Ether Phenyl Glycidyl Ether 5
Phenylenediamine and its salts o-Phenylenediamine and its salts 26 (o-Phenylenediamine)
44 (o-Phenylenediamine dihydrochloride)
Phenylhydrazine Phenylhydrazine and its salts 1 (Phenylhydrazine)
1.4 (Phenylhydrazine hydrochloride)
Phenylphenate, Sodium o-Phenylphenate, Sodium 200
Poligeenan (Polygeenan) Polygeenan 1200
Polybrominated Biphenyls Polybrominated biphenyls 0.02
Polychlorinated Biphenyls Polychlorinated Biphenyls 0.099
Ponceau 3R Ponceau 3R 40
Ponceau MX Ponceau MX 200
Potassium Bromate Potassium bromate 1
Potassium Dimethyldithiocarbamate Potassium dimethyldithiocarbamate 720
Procarbazine Procarbazine 0.05
Procarbazine Hydrochloride Procarbazine hydrochloride 0.06
Propane Sultone 1,3-Propane Sultone 0.3
Propazine Propazine 100 (oral)
Propiolactone beta-Propiolactone 0.05
Propyleneimine 2-Methylaziridine (Propyleneimine) 0.028
Propylthiouracil Propylthiouracil 0.7
Quizalofop-ethyl Quizalofop-ethyl 590
Reserpine Reserpine 0.06
Safrole Safrole 3
Simazine Simazine 100 (oral)
Sodium dimethyldithiocarbamate Sodium dimethyldithiocarbamate 23 (oral)
58 (oral) as a 40% pesticidal formulation
Sterigmatocystin Sterigmatocystin 0.02
Streptozotocin Streptozotocin (Streptozocin) 0.006
Styrene Styrene 27
Styrene Oxide Styrene Oxide 4
Sulfallate Sulfallate 4
Sulfur Dioxide Sulfur Dioxide 10,000
Tetrachlorodibenzo-p-dioxin and related compounds 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 0.000005
Tetrachloroethane 1,1,2,2-Tetrachloroethane 3
Tetrachloroethylene Tetrachloroethylene (Perchloroethylene) 14
Tetramethyldiaminodiphenylmethane 4,4'-Methylene bis(N,N-dimethyl)benzenamine 20
Tetranitromethane Tetranitromethane 0.059
Thioacetamide Thioacetamide 0.1
Thiodianiline 4,4'-Thiodianiline 0.05
Thiophanate Methyl Thiophanate Methyl 600 (oral)
Thiourea Thiourea 10
Titanium dioxide (airborne, unbound particles of respirable size) Titanium dioxide (airborne, unbound particles of respirable size) 440 micrograms per day for airborne, unbound titanium dioxide particles with diameters of 10 micrometers or less
 44 micrograms per day for airborne, unbound titanium dioxide particles with diameters of 0.8 micrometers or less
Toluene Toluene 7000 ᶜ
Toluene Diisocyanates Toluene Diisocyanate 20
Toluidine o-Toluidine 4
Toluidine Hydrochloride o-Toluidine Hydrochloride 5
Toxaphene Toxaphene (Polychlorinated camphenes) 0.6
trans-2[(Dimethylamino)-methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1-3-4-oxadiazole trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole 2
Trichloroacetic Acid Trichloroacetic Acid 9.9
Trichloroethane Vinyl trichloride (1,1,2-Trichloroethane) 10
Trichloroethylene Trichloroethylene 14 (oral)
50 (inhalation)
Trichlorophenol 2,4,6-Trichlorophenol 10
Trimethyl Phosphate Trimethyl Phosphate 24
Trinitrotoluene 2,4,6-Trinitrotoluene 8.2
Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) 5.4
Tris(1-aziridinyl)phosphine Sulfide Tris(1-aziridinyl)phosphine Sulfide (Thiotepa) 0.06
Tris(2-3-dibromopropyl)phosphate Tris(2,3-dibromopropyl)phosphate 0.3
Trp-P-1 (Tryptophan-P-1) Trp-P-1 (Tryptophan-P-1) 0.03
Trp-P-2 (Tryptophan-P-2) Trp-P-2 (Tryptophan-P-2) 0.2
Urethane Urethane (Ethyl Carbamate) 0.7
Vinyl chloride Vinyl chloride 3
Xylidine 2,6-Xylidine (2,6-Dimethylaniline) 110

a Where a source or product results in exposures by multiple routes, the total exposure must be considered. For example, the MADL for benzene is exceeded when the absorbed dose exceeds 24 μg/day. If only inhalation and oral exposure occurs, the benzene MADL is exceeded when: (oral dose ÷ 24 μg/day) + (inhalation dose ÷ 49 μg/day) > 1.0.

b Levels for male children and adolescents were calculated by application of the default bodyweights specified in Section 25703(a)(8) to the procedure specified in Sections 25801 and 25803, Title 27, California Code of Regulations.

c Level represents absorbed dose (rounded from 6,525 μg/day). Since 100% of ingested toluene is absorbed, oral dose is equivalent to administered dose. It is assumed that roughly 50% of the dose administered by the inhalation route is absorbed. Therefore the MADL for inhaled toluene is 13,000 μg/day (rounded from 13,050 μg/day ), corresponding to an absorbed dose of 6,525 μg/day.

d Fibers equal to or greater than 5 micrometers in length and 0.3 micrometers in width, with a length to width ratio of greater than or equal to 3:1 as measured by phase contrast microscopy.