N-Methylpyrrolidone

Chemical Status

Reproductive Toxicity:	Currently listed

Chemical Listing Details

Reproductive Toxicity

Listed as causing:	Developmental Toxicity
Developmental Toxicity
Date of Listing:	06/15/2001
Basis for Listing:	Authoritative Bodies-US Environmental Protection Agency

Safe Harbor Levels

Reproductive Toxicity
Maximum Allowable Dose Level (MADL) - Inhalation:	3200 µg/day
Maximum Allowable Dose Level (MADL) - Oral:	17000 (dermal) µg/day

Documents, Presentations, and Publications

Reproductive Toxicity:	Maximum Allowable Dose Levels for N-Methylpyrrolidone (Dermal and Inhalation Exposures) Listing Notice - N-Methylpyrrolidone June 15, 2001 Notice of Intent to List - N-Methylpyrrolidone June 25, 1999 Package 14a - Chemicals meeting the criteria for listing as DARTs via the AB Mechanism - 4 Chemicals June 25, 1999

Public Notices Related to this Chemical

• Prioritization: Chemicals for Consultation by the Carcinogen Identification Committee
• Amendment to Section 12805. Specific Regulatory Levels: Reproductive Toxicants (2,4-D butyric acid, m-dinitrobenzene, hydramethylnon and N-methylpyrrolidone)
• Notice of Revised Time for the Public Hearing for Proposed Amendments to Title 22, California Code of Regulations, Section 12805, Specific Regulatory Levels: Chemicals Causing Reproductive Toxicity
• Notice of Proposed Rulemaking: Amendment to Section 12805, Specific Regulatory Levels: 2,4-D Butyric Acid, m-Dinitrobenzene, Hydramethylnon and N-Methylpyrrolidone
• December 17, 2001 Meeting of the Science Advisory Board's Developmental and Reproductive Toxicant (DART) Identification Committee
• Chemical Listed Effective June 15, 2001 as Known to the State to Cause Reproductive Toxicity: N-Methylpyrrolidone
• Notice of Intent to List: N-Methylpyrrolidone
• Notice of Intent to List: Avermectin B1, Delta isomer of avermectin B1, N-Methylpyrrolidone, and Imazalil
• Chemicals Meeting the Critieria for Listing as Developmental and Reproductive Toxicants (DARTs) Via the Authoritative Bodies Mechanism: 4 Chemicals Identified By U.S. EPA
• Request for Information, 16 Chemicals Under Consideration for Possible Listing Via the Authoritative Bodies Mechanisms

Meetings

• Carcinogen Identification Committee Meeting Scheduled for October 12 and 13, 2011
• Revised Agenda for the December 17, 2001 Meeting of the Science Advisory Board's Developmental and Reproductive Toxicant (DART) Identification Committee
• Tentative Agenda for the December 17, 2001 Meeting of the Science Advisory Board's Developmental and Reproductive Toxicant (DART) Identification Committee