Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The proposition protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update a list of chemicals known to the state to cause cancer or reproductive toxicity.

Questions?

Questions about Proposition 65? Check our Frequently asked Questions page or visit our Proposition 65 Warnings website

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

February 21, 2020: Issuance of Safe Use Determination for Exposures to Crystalline Silica From The Use of Four WOODWISE® Products

OEHHA received a request for a Safe Use Determination (SUD) for exposures to crystalline silica in four Woodwise® wood filler products. The request was made by Design Hardwood Products, Inc. (DHPI), pursuant to Title 27 of the California Code of Regulations, section 25204(b)(3).

January 31, 2020: Notice of Proposed Rulemaking: Article 6 Clear and Reasonable Warnings Sections 25602, 25607, 25607.1, and 25607.3

The proposed amendment is to clarify certain provisions of the regulations addressing consumer product exposure warnings, specific product, chemical and area exposure warnings, food exposure warnings, and alcoholic beverage exposure warnings. This notice also opens a comment period that will close on March 16, 2020.

January 23, 2020: Chemicals Listed Effective January 3, 2020 As Known to The State of California To Cause Reproductive Toxicity (Developmental Endpoint): Cannabis (Marijuana) Smoke and Δ9-Tetrahydrocannabinol (Δ9-THC)

At a public meeting on December 11, 2019, the Developmental and Reproductive Toxicant Identification Committee in its official capacity as the “state’s qualified experts” determined that cannabis (marijuana) smoke and Δ9-tetrahydrocannabinol (Δ9-THC) were shown to cause reproductive toxicity based on the developmental endpoint.

January 14, 2020: Notice of Amendments – Article 6 Clear and Reasonable Warnings, Section 25600.2, Responsibility to Provide Consumer Product Exposure Warnings

On December 31, 2019, the Office of Administrative Law approved amendments to Title 27, California Code of Regulations, section 25600.2, subsections (b), (c), (f) and (i), Responsibility to Provide Consumer Product Exposure Warnings.

January 3, 2020: Proposition 65 Interpretive Guideline No. 2020-01, Residential Exposure to Dichlorvos

The Office of Environmental Health Hazard Assessment (OEHHA) announces the availability of n Proposition 65 interpretive guideline for residential exposure to dichlorvos (DDVP) in naled bait stations and lures during invasive pest eradication program activities.