Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The proposition protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update a list of chemicals known to the state to cause cancer or reproductive toxicity.

Questions?

Questions about Proposition 65? Check our Frequently asked Questions page or visit our Proposition 65 Warnings website

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated December 29, 2023

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, which interprets and applies Proposition 65 and its implementing regulations to a specific set of facts in response to a request by a business or a trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 and its implementing regulations, as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties.

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

Dec 29, 2021: Notice to Interested Parties Chemicals Listed Effective December 31, 2021 As Known to the State of California to Cause Reproductive Toxicity: Perfluorononanoic Acid (PFNA) and Its Salts
Effective December 31, 2021, the Office of Environmental Health Hazard Assessment (OEHHA) is adding Perfluorononanoic acid (PFNA) and its salts to the list of chemicals known to the state to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).
Dec 22, 2021: Notice to Interested Parties Chemicals Listed Effective December 24, 2021 As Known to the State of California to Cause Cancer: Perfluorooctane Sulfonic Acid (PFOS) and Its Salts and Transformation and Degradation Precursors
Effective December 24, 2021, the Office of Environmental Health Hazard Assessment (OEHHA) is adding perfluorooctane sulfonic acid (PFOS) and its salts and transformation and degradation precursors to the list of chemicals known to the state to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65)
Dec 17, 2021: Notice to Interested Parties Chemicals Listed Effective December 17, 2021 As Known to the State of California to Cause Cancer: Tetrahydrofuran; 2-ethylhexyl Acrylate; Methyl Acrylate; and Trimethylolpropane Triacrylate, Technical Grade
Effective December 17, 2021, the Office of Environmental Health Hazard Assessment (OEHHA) is adding tetrahydrofuran (CAS No. 109-99-9), 2-ethylhexyl acrylate (CAS No. 103-11-7), methyl acrylate (CAS No. 96-33-3), and trimethylolpropane triacrylate, technical grade to the list of chemicals known to the State of California to cause cancer for purposes of Proposition 65
Dec 3, 2021: Preliminary Agenda for Meeting of the Developmental and Reproductive Toxicant Identification Committee
The preliminary agenda for the meeting of the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for possible listing of perfluorononanoic acid (PFNA) and its salts, and perfluorodecanoic acid (PFDA) and its salts, under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65) is given. The order of items on the agenda is provided for general reference only and is subject to change at the discretion of the Committee Chair.

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