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Chlorinated dibenzo-p dioxins and dibenzofurans

Chronic Inhalation REL (μg/m3)
0.00004 (inhalation); 0.00001 μg/kg BW-day (oral)
Chronic Target Organs
Inhalation and oral: Alimentary system (liver); reproductive system; development; endocrine system; respiratory system; hematologic system
Human Data
No
Last Chronic REL Revision
12/01/2008
Last Acute REL Revision
12/01/2008

Toluene

Acute REL (μg/m3)
5000
Species
Human
Acute REL Toxicologic Endpoint
Headache, dizziness, slight eye and nose irritation
Acute REL Target Organs
Nervous system; eyes; respiratory system
8-Hour Inhalation REL (μg/m3)
830
Last 8-Hour REL Revision
August, 2020
Chronic Inhalation REL (μg/m3)
420
Chronic Target Organs
Acquired color vision impairment (dyschromatopsia)
Human Data
Yes
Last Chronic REL Revision
2020
8-Hour Reference Exposure Levels Comments
Acute Reference Exposure Levels Comments
Last Acute REL Revision
2020

Ethylene Glycol Monoethyl Ether Acetate

Acute REL (μg/m3)
140
Species
Rabbit
Acute REL Toxicologic Endpoint
Reproductive/ development (teratogenic effects in rabbits); headache, nausea
Acute REL Target Organs
Reproductive/ development, nervous system
Chronic Inhalation REL (μg/m3)
300
Chronic Target Organs
Development
Human Data
No
Last Chronic REL Revision
2000
Severity
Severe
Last Acute REL Revision
1999

Triethylamine

Acute REL (μg/m3)
2800
Species
Human
Acute REL Toxicologic Endpoint
Visual disturbances, eye irritation
Acute REL Target Organs
Nervous system; eyes
Chronic Inhalation REL (μg/m3)
200
Chronic Target Organs
Eyes
Human Data
No
Last Chronic REL Revision
2002
Severity
Mild
Last Acute REL Revision
1999

Nickel Subsulfide

Acute REL (μg/m3)
0.2
Species
Mouse
Acute REL Toxicologic Endpoint
Depressed antibody response
Acute REL Target Organs
Immune system
8-Hour Inhalation REL (μg/m3)
0.06
Last 8-Hour REL Revision
2012
Chronic Inhalation REL (μg/m3)
0.014 (inhalation); 11 μg/kg BW-day (oral)
Chronic Target Organs
Inhalation: Respiratory system, hematologic system. Oral: Development
Human Data
No
Last Chronic REL Revision
2012
Chronic Reference Exposure Levels Comments

Inhalation concentrations as micrograms Ni/m3; oral dose as micrograms Ni/kg-day.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds (except nickel oxide for chronic inhalation exposures).

8-Hour Reference Exposure Levels Comments

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. Listed as Nickel & nickel compounds.

Acute Reference Exposure Levels Comments

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds.

Last Acute REL Revision
2012