Nickel and Nickel Compounds
Acute REL (μg/m3)
0.2
Species
Mouse
Acute REL Toxicologic Endpoint
Depressed antibody response
Acute REL Target Organs
Immune system
8-Hour Inhalation REL (μg/m3)
0.06
Last 8-Hour REL Revision
2012
Chronic Inhalation REL (μg/m3)
0.014 (inhalation); 11 μg/kg BW-day (oral)
Chronic Target Organs
Inhalation: Respiratory system, hematologic system. Oral: Development
Human Data
No
Last Chronic REL Revision
2012
Chronic Reference Exposure Levels Comments
Inhalation concentrations as micrograms Ni/m3; oral dose as micrograms Ni/kg-day.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds (except nickel oxide for chronic inhalation exposures).
8-Hour Reference Exposure Levels Comments
Inhalation concentrations as micrograms Ni/m3.
OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. Listed as Nickel & nickel compounds.
Acute Reference Exposure Levels Comments
Inhalation concentrations as micrograms Ni/m3.
OEHHA 2012. Nickel Reference Exposure Levels.
Last Acute REL Revision
2012