Streptozotocin

CAS Number

18883-66-4

Synonym

2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-d-glucose; NCI-C03167; STR; Streptozocin; Streptozoticin; STRZ; STZ; Zanosar

Occurrence/Use

Medicine (antibiotic, chemotherapeutic agent). Naturally produced by Streptomyces achromogenes

Cancer Potency Information

Latest Criteria: Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 3.1 E-2
Inhalation Slope Factor (mg/kg-day)-1: 1.1 E+2
Oral Slope Factor (mg/kg-day)-1: 1.1 E+2
Comments/References:

OEHHA 1992. Expedited Cancer Potency Values and Proposed Regulatory Levels for Certain Proposition 65 Carcinogens.

Proposition 65

Chemical Status

Cancer: Currently listed
Reproductive Toxicity : Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Reproductive Toxicity

Date of Listing
Listed as causing: Developmental Toxicity Male Reproductive Toxicity Female Reproductive Toxicity
Developmental Toxicity
Date of Listing:
Basis for Listing : Formally Required
Male Reproductive Toxicity
Date of Listing:
Basis for Listing : Formally Required
Female Reproductive Toxicity
Basis for Listing: Formally Required

Safe Harbor Levels

No Significant Risk Level (NSRL)
0.006 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer:
Reproductive Toxicity:

Public notices related to this chemical