Chemicals Listed Effective August 20, 1999

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Chemicals Listed Effective August 20, 1999 as Known to the State of California to Cause Cancer or Reproductive Toxicity

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is adding the 20 chemicals named below to the list of chemicals known to the State to cause cancer or reproductive toxicity, for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65 or the Act). The chemicals are listed effective August 20, 1999 pursuant to the administrative listing mechanisms provided under the Act, based upon either (1) a formal identification by an authoritative body that the chemical causes cancer or reproductive toxicity, or (2) a formal requirement by a state or federal agency that the chemical be labeled or identified as causing reproductive toxicity. Regulations governing the listing of chemicals under the "authoritative bodies" mechanism and the "formally required to be labeled or identified" mechanism are published in Title 22, California Code of Regulations (22 CCR), Sections 12306 and 12902, respectively.

The reader is directed to the Notice of Intent to List Chemicals published in the March 19, 1999 issue of the California Regulatory Notice Register for the supporting documentation which OEHHA relied upon in making its determination that the criteria for administrative listing had been satisfied. A complete, updated chemical list is published elsewhere in this issue of the California Regulatory Notice Register.

The chemicals being listed under Proposition 65 as known to cause cancer and the mechanism under which each is listed are shown below:

Chemical CAS No. Listing Mechanism1
Oxythioquinox 2439-01-2 AB
Primidone 125-33-7 AB
Thiodicarb 59669-26-0 AB
Vinclozolin 50471-44-8 AB

 

The chemicals being listed under Proposition 65 as known to cause reproductive toxicity and the mechanism under which each is listed are shown below:

Chemical CAS No. Toxicological Endpoint Listing Mechanism1
2,4-Dinitrotoluene 121-14-2 male reproductive toxicity AB
2,6-Dinitrotoluene 606-20-2 male reproductive toxicity AB
Technical Grade Dinitrotoluene --- female reproductive toxicity
male reproductive toxicity
AB
Heptachlor 76-44-8 developmental toxicity AB
Acetazolamide 59-66-5 developmental toxicity FR
Altretamine 645-05-6 developmental toxicity
male reproductive toxicity
FR
Etodolac 41340-25-4 developmental toxicity
female reproductive toxicity
FR
Flurbiprofen 5104-49-4 developmental toxicity
female reproductive toxicity
FR
Gemfibrozil 25812-30-0 male reproductive toxicity
female reproductive toxicity
FR
Halobetasol propionate 66852-54-8 developmental toxicity FR
Idarubicin hydrochloride --- developmental toxicity
male reproductive toxicity
FR
Mebendazole 31431-39-7 developmental toxicity FR
Pimozide 2062-78-4 developmental toxicity
female reproductive toxicity
FR
Prednisolone sodium phosphate 125-02-0 developmental toxicity FR
Sermorelin acetate --- developmental toxicity FR
Streptozocin 18883-66-4 developmental toxicity
male reproductive toxicity
female reproductive toxicity
FR

1 Listing mechanism:
AB – "authoritative bodies" mechanism (22 CCR Section 12306)
FR – "formally required to be labeled or identified" mechanism (22 CCR Section 12902)