Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65? Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

October 19, 2018: Notice of Public Hearing and Extension of Public Comment Period on Proposed Amendment to Sections 25821(a) and (c) Level of Exposure to Chemicals Causing Reproductive Toxicity: Calculating Intake by the Average Consumer of a Product

OEHHA is extending the public comment period on this proposed amendment to 5:00 pm, Monday, November 26, 2018 and has scheduled a public hearing on Monday, November 19, 2018.

October 5, 2018: Notice of Intent to list Bevacizumab

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list bevacizumab as known to the state to cause reproductive toxicity (developmental and female endpoints) under the Safe Drinking Water and Toxic Enforcement Act of 198.

October 5, 2018: Proposed Amendment to Sections 25821(a) and (c) Level of Exposure to Chemicals Causing Reproductive Toxicity: Calculating Intake by the Average Consumer of a Product

This proposed regulatory action would amend subsection (a) to clarify that where a business presents evidence for the “level in question” of a chemical listed as causing reproductive toxicity in a food product based on the average of multiple samples of that food, the level in question may not be calculated by averaging the concentration of the chemical in food products from different manufacturers or producers, or that were manufactured in different facilities from the product at issue.

September 28, 2018: Notice of Proposed Rulemaking: Title 27, California Code of Regulations - Amendment to Section 25805 Specific Regulatory Levels: Chemicals Causing Reproductive Toxicity n-Hexane

Proposal to adopt Proposition 65 Maximum Allowable Dose Levels (MADLs) for n-hexane. The proposed oral MADL for n-hexane is 28,000 micrograms per day and the proposed inhalation MADL for n-hexane is 20,000 micrograms per day.

August 17, 2018: Acceptance of a Request for a Safe Use Determination for Styrene in Fiber Care Baths, Inc. Bathware Products Manufactured Utilizing 1st and 2nd Laminations Systems and LV-9800 Acrylated Gel-Coat and Opportunity for Public Comment

This SUD request is limited to exposures to styrene from Fiber Care Baths, Inc. bathware products manufactured utilizing 1st and 2nd laminations systems and application of the LV-9800 acrylated gel-coat. Exposure to other listed substances, if any, which may be present in these materials will not be reviewed by OEHHA in the context of this request.