Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65?  Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated December 08, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

Notice that Office of Environmental Health Hazard Assessment (OEHHA) proposes to establish a specific regulatory level having no observable effect for acrylamide. The proposed MADL is 140 micrograms per day.  Request for comments.

Notice of proposed rulemaking regarding specific regulatory levels posing no significant risk: p-chloroaniline and p-chloroaniline hydrochloride.

February 2010 request for relevant information on Bisphenol-A  as a reproductive toxicant for listing by the Authoritative Bodies mechanism.

Comment period. BPA appears to meet the criteria for listing as known to the State to cause reproductive toxicity under Proposition 65, based on findings of the National Toxicology Program’s Center for the Evaluation of Risks to Human Reproduction.

Public comment period for the hazard ID materials for Fluoride and Its Salts, and Tris(1,3-Dichloro-2-Propyl) Phosphate.  Both will be considered for listing at the October 2011 meeting.