Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The law protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update the list of chemicals subject to the law’s requirements.

Questions about Proposition 65? Visit our Proposition 65 Warnings website.

Proposition 65 Resources

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated January 03, 2025

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops

Notices

All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations

Warnings

Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, interpreting and applying Proposition 65 regulations to specific facts in response to a request by a business or trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 regulations as applied to specific facts

Information Letters

Letters about Proposition 65's application from OEHHA to interested parties

Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)

Reports, Notices, Documents

March 5, 2021: Notice of Public Hearing and Extension of Public Comment Period: Amendments to Article 6, Clear and Reasonable Warnings Short-form Warnings

OEHHA has scheduled a public hearing on March 11, 2021, at 10:00 a.m. The hearing will be conducted remotely and the public comment period for this regulatory action is being extended to March 29, 2021, to accommodate the hearing. There are two ways that you can view the Public Hearing on Proposed Amendments to Regulations under Article 6 – Short Form Warnings.

January 26, 2021: Notice of Adoption of Amendments to Article 6 Clear and Reasonable Warnings Sections 25602, 25607, 25607.1, and 25607.3

Substantive changes relate to the methods for providing warnings for alcoholic beverages purchased over the internet or through mobile apps.

January 20, 2021: November 17, 2020 Virtual Meeting of the Carcinogen Identification Committee

OEHHA will be using the GoToWebinar platform for this meeting. If you wish to provide oral public comments at the meeting, you must register as an attendee. While we encourage advance registration and request that registered attendees join the webinar at least 5 minutes before the 10:00 am meeting start time, registration will not close until after the meeting is adjourned.

December 18, 2020: Notice to Interested Parties Developmental Toxicity Endpoint Reinstated for the Listing of Bisphenol A (BPA) as Known to the State of California to Cause Reproductive Toxicity

Effective December 18, 2020, the Office of Environmental Health Hazard Assessment (OEHHA) is adding the developmental endpoint to the existing reproductive toxicity (female endpoint) listing of bisphenol A (BPA) (CAS RN. 80-05-7) on the Proposition 65 list of chemicals known to the State to cause cancer or reproductive toxicity. The listing now includes an additional endpoint, developmental toxicity.

December 15, 2020: Amendment to Section 25705 Specific Regulatory Levels Posing No Significant Risk: p-Chloro-α,α,α-Trifluorotoluene

Proposition 65 No Significant Risk Level (NSRL) of 23 micrograms per day for the chemical p-chloro-α,α,α-trifluorotoluene (PCBTF). The regulation will be effective on April 1, 2021.