OEHHA added glyphosate to the Proposition 65 list of carcinogens in July 2017, based on a finding by the World Health Organization’s International Agency for Research on Cancer (IARC) that glyphosate is both an animal carcinogen and “probably carcinogenic to humans”.
Proposition 65
Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The proposition protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.
Proposition 65 requires the state to maintain and update a list of chemicals known to the state to cause cancer or reproductive toxicity.
Questions?
Questions about Proposition 65? Check our Frequently asked Questions page or visit our Proposition 65 Warnings website
About Proposition 65
The Safe Drinking Water and Toxic Enforcement Act
The Proposition 65 List
The current Proposition 65 list is dated December 29, 2023
Meetings, Hearings and Workshops
Upcoming and past meetings, hearings and workshops
Notices
All Proposition 65 Notices
Laws and Regulations
Links and downloads related to Proposition 65 statute and regulations
Warnings
Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List
How chemicals are added to the Proposition 65 list
Learn how chemicals are added to the list
Safe Use Determinations
A Safe Use Determination (SUD) is a written statement issued by OEHHA, which interprets and applies Proposition 65 and its implementing regulations to a specific set of facts in response to a request by a business or a trade group
Interpretive Guidelines for Proposition 65
An Interpretive Guideline interprets Proposition 65 and its implementing regulations, as applied to specific facts
Information Letters
Letters about Proposition 65's application from OEHHA to interested parties.
Warning Regulations
Clear and reasonable warnings
Searchable Proposition 65 Chemical Database
Search the Proposition 65 Chemical Database
Safe harbor levels
Proposition 65 No Significant Risk Levels (NSRLs) and Maximum Allowable Dose Levels (MADLs)
Reports, Notices, Documents
This rulemaking adds Sections 25607.36 and 25607.37 to Article 6 as safe harbor tailored warnings for exposures to listed chemicals that may occur through the rental of a motor vehicle.
OEHHA is requesting comments on the modifications to the regulatory text. In order to be considered, OEHHA must receive comments by August 5, 2019, which is the designated close of the comment period. All comments will be posted on the OEHHA website at the close of the public comment period.
OEHHA intends to list the following chemicals as known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). This action is being proposed pursuant to the “Labor Code” listing mechanism. OEHHA has determined that 2-Amino-4-chlorophenol, 2-Chloronitrobenzene, 1,4-Dichloro-2-nitrobenzene, 2,4-Dichloro-1-nitrobenzene, N,N-Dimethylacetamide, and para-Nitroanisole meet the criteria for listing as known to cause cancer by this mechanism. OEHHA is providing an opportunity to comment, and comments must be received by Monday, August 12, 2019 to be considered. Additional information can be found in the listing notice.
The listing of p-chloro-α,α,α-trifluorotoluene is based on formal identification by the National Toxicology Program (NTP), an authoritative body, that the chemical causes cancer.