Chemical Listed Effective April 20, 2007 as Known to the State of California to Cause Reproductive Toxicity: di-isodecyl phthalate (DIDP)

Chemical Listed Effective April 20, 2007 as Known to the State of California to Cause Reproductive Toxicity: di-isodecyl phthalate (DIDP) Current List of Proposition 65 Chemicals

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is adding di-isodecyl phthalate (DIDP) (CAS No. 68515-49-1 and 26761-40-0) to the list of chemicals known to the state to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Health and Safety Code section 25249.5 et seq., commonly known as Proposition 65). The listing of di-isodecyl phthalate (DIDP) is effective April 20, 2007.

Di-isodecyl phthalate (DIDP) (CAS No. 68515-49-1 and 26761-40-0) is being listed as a chemical known to the State of California to cause developmental toxicity. The listing of this chemical is based on formal identification by an authoritative body, in this case, the National Toxicology Program, in final reports of the National Toxicology Program’s Center for the Evaluation of Risks to Human Reproduction (“NTP-CERHR”) which conclude that the chemical causes developmental toxicity. The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 22, Cal. Code of Regs., section 12306.

The reader is directed to the Notice of Intent to List di-isodecylphthalate (DIDP) (CAS Nos. 68515-49-1 and 26761-40-0) published in the March 4, 2005 issue of the California Regulatory Notice Register (Register 2005, No. 9-Z) for the documentation supporting OEHHA’s determination that the criteria for administrative listing have been satisfied for this chemical.

OEHHA analysis of dose-response data to establish the maximum allowable dose level (MADL) for di-isodecyl phthalate (DIDP) (CAS No. 68515-49-1 and 26761-40-0) under Proposition 65 has not yet been conducted. The priority status for the development of such analysis will be announced in a future OEHHA Proposition 65 Status Report for Safe Harbor Levels, available at /proposition-65.

Summary of Listing Criteria

Chemical CAS # Toxicological Endpoint Listing Mechamism1
Di-isodecyl phthalate (DIDP) 68515-49-1
26761-40-0
Developmental toxicity AB

1 Listing mechanism: AB – “authoritative bodies” mechanism (Title 22, Cal. Code of Regs. section 12306)