Toluene
CAS Number
108-88-3Synonym
Antisal 1A; Anisen; Caswell No. 859; CP 25; Methacide; Methylbenzene; Methylbenzol; NCI-C07272; Phenylmethane; Toluol
Occurrence/Use
Solvent, jet fuel component and gasoline additive, cement for polystyrene kits; production of polymers; chemical intermediate (benzene dealkylation); component of car exhaust and tobacco smoke
Soil Screening
| Last CHHSL revision: | 1/2005 |
|---|---|
| CHHSL Comments: |
For chemical-specific screening levels for use in assessing contaminated sites, please see HHRA Note 3 (DTSC HERO). https://www.dtsc.ca.gov/assessingrisk/humanrisk2.cfm |
Cancer Potency Information
| Latest Criteria: | Chronic Reference Exposure Levels |
|---|
Air
Acute RELs
| Acute REL (μg/m3): | 5000 |
|---|---|
| Species: | Human |
| Acute REL Toxicologic Endpoint: | Headache, dizziness, slight eye and nose irritation |
| Acute REL Target Organs: | Nervous system; eyes; respiratory system |
| Last Acute REL Revision: | 2020 |
| Acute Reference Exposure Levels Comments: |
8-Hour RELs
| 8-Hour Inhalation REL (μg/m3): | 830 |
|---|---|
| Last 8-Hour REL Revision: | August, 2020 |
| 8-Hour Reference Exposure Levels Comments: |
Chronic REL
| Chronic Inhalation REL (μg/m3): | 420 |
|---|---|
| Chronic Target Organs: | Acquired color vision impairment (dyschromatopsia) |
| Human Data: | Yes |
| Last Chronic REL Revision: | 2020 |
| Chronic Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3
|
Proposition 65
Chemical Status
| Reproductive Toxicity : | Currently listed |
|---|
Reproductive Toxicity
| Listed as causing: | Developmental Toxicity | Developmental Toxicity |
|---|---|
| Date of Listing: | |
| Basis for Listing : | State's Qualified Experts | Female Reproductive Toxicity |
| Date of Delisting: | |
| Basis for Listing: | Labor Code |
Safe Harbor Levels
| Reproductive Toxicity | |
| Maximum Allowable Dose Level (MADL) - Inhalation: | 13000 µg/day |
|---|---|
| Maximum Allowable Dose Level (MADL) - Oral: | 7000 µg/day |
Comments
Public notices related to this chemical
- Change in the Identification of Reproductive Toxicity Endpoints in the Listing of Toluene as Known to Cause Reproductive Toxicity
- Chemicals Listed Effective August 7, 2009 as Known to the State of California to Cause Cancer or Reproductive Toxicity
- Chemicals Proposed for Listing by the Labor Code Mechanism (Reproductive and Developmental Toxicants)
- Final Statement of Reasons - Reproductive Toxicants: Toluene
Water
California Public Health Goals Data
| Health Risk Category: | Hepatotoxicity (liver), endocrine toxicity (thymus) |
|---|---|
| Public Health Goal (mg/L): | 0.15 |
| Public Health Goal - Download: | toluf.pdf |
| Cancer Risk at PHG: | n/a |
| MCL value (mg/L): | 0.15 |
| Cancer Risk at MCL: | n/a |
| Last PHG Revision : | 1999 |
| California PHG Comments: | OEHHA 2013. Health Risk Information for Public Health Goal Exceedance Reports |
Female reproductive toxicity endpoint removed from listing for toluene effective March 7, 2014.