Tetrachloroethylene
CAS Number
127-18-4Synonym
AI3-01860; Ankilostin; Antisal 1; Antisol 1; Caswell No. 827; Didakene; Ethylene Tetrachloride; NCI-C04580; Nema; PCE; Perchlor; Perchloroethylene; PERC; Perclene; Perklone; Tetracap; Tetrachloroethylene; Tetrachloroethene; Tetraleno; Tetralex; Tetropil; EPA Pesticide Code: 078501
Occurrence/Use
Solvent for organic materials used in dry-cleaning, textile processing, and vapor-degreasing; chemical intermediate. Formerly used in medicine as a hookworm vermifuge.
Soil Screening
| Last CHHSL revision: | 1/2005 |
|---|---|
| CHHSL Comments: |
For chemical-specific screening levels for use in assessing contaminated sites, please see HHRA Note 3 (DTSC HERO). https://www.dtsc.ca.gov/assessingrisk/humanrisk2.cfm |
Cancer Potency Information
| Inhalation Unit Risk (μg/cubic meter)-1: | 6.1 E-6 |
|---|---|
| Inhalation Slope Factor (mg/kg-day)-1: | 2.1 E-2 |
| Oral Slope Factor (mg/kg-day)-1: | 5.4 E-1 |
| Last Cancer Potency Revision: | 09/08/2016 |
| Comments/References: |
Listed as Perchloroethylene. (OEHHA 2016) Notice of Adoption of Inhalation Cancer Unit Risk Factor for Perchloroethylene (OEHHA 2016) Perchloroethylene Unit Risk Factor – Review Draft for Scientific Review Panel on Toxic Air Contaminants (OEHHA 2009) Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. (OEHHA 2001) Public Health Goal for Tetrachloroethylene in Drinking Water. (ARB/OEHHA 1991) Toxic Air Contaminant Identification Report: Perchloroethylene. (OEHHA 1988) Proposition 65 NSRL is based on the human cancer potency value of 0.05 (mg/kg-day)-1
|
Air
Acute RELs
| Acute REL (μg/m3): | 20000 |
|---|---|
| Species: | Human |
| Acute REL Toxicologic Endpoint: | Nervous system, respiratory system, eyes |
| Acute REL Target Organs: | Nervous system, respiratory system, eyes |
| Severity: | Mild |
| Last Acute REL Revision: | 1999 |
| Acute Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D2. |
Chronic REL
| Chronic Inhalation REL (μg/m3): | 35 |
|---|---|
| Chronic Target Organs: | Alimentary system (liver), kidney |
| Human Data: | No |
| Last Chronic REL Revision: | 1991 |
| Chronic Reference Exposure Levels Comments: |
Proposition 65
Chemical Status
| Cancer: | Currently listed |
|---|
Cancer
Cancer - Listing Mechanism
State's Qualified Experts
| Listed as causing : | Listed as causing: Cancer |
|---|---|
| Date of Listing: |
Safe Harbor Levels
No Significant Risk Level (NSRL)
14 µg/day
| Cancer |
Water
California Public Health Goals Data
| Health Risk Category: | Carcinogenicity |
|---|---|
| Public Health Goal (mg/L): | 0.00006 |
| Public Health Goal - Download: | pceaug2001.pdf |
| Cancer Risk at PHG: | 0.000001 |
| MCL value (mg/L): | 0.005 |
| Cancer Risk at MCL: | 0.00008 |
| Last PHG Revision : | 2001 |
| California PHG Comments: | OEHHA 2013. Health Risk Information for Public Health Goal Exceedance Reports |