Tetrachloroethylene

CAS Number

127-18-4

Synonym

AI3-01860; Ankilostin; Antisal 1; Antisol 1; Caswell No. 827; Didakene; Ethylene Tetrachloride; NCI-C04580; Nema; PCE; Perchlor; Perchloroethylene; PERC; Perclene; Perklone; Tetracap; Tetrachloroethylene; Tetrachloroethene; Tetraleno; Tetralex; Tetropil; EPA Pesticide Code: 078501

Occurrence/Use

Solvent for organic materials used in dry-cleaning, textile processing, and vapor-degreasing; chemical intermediate. Formerly used in medicine as a hookworm vermifuge.

Tetrachloroethylene

Soil Screening

Last CHHSL revision: 1/2005
CHHSL Comments:

For chemical-specific screening levels for use in assessing contaminated sites, please see HHRA Note 3 (DTSC HERO). https://www.dtsc.ca.gov/assessingrisk/humanrisk2.cfm

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 6.1 E-6
Inhalation Slope Factor (mg/kg-day)-1: 2.1 E-2
Oral Slope Factor (mg/kg-day)-1: 5.4 E-1
Last Cancer Potency Revision: 09/08/2016
Comments/References:

Listed as Perchloroethylene.

(OEHHA 2016) Notice of Adoption of Inhalation Cancer Unit Risk Factor for Perchloroethylene

(OEHHA 2016) Perchloroethylene Unit Risk Factor – Review Draft for Scientific Review Panel on Toxic Air Contaminants

(OEHHA 2009) Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

(OEHHA 2001) Public Health Goal for Tetrachloroethylene in Drinking Water.

(ARB/OEHHA 1991) Toxic Air Contaminant Identification Report: Perchloroethylene.

(OEHHA 1988) Proposition 65 NSRL is based on the human cancer potency value of 0.05 (mg/kg-day)-1

 

Air

Acute RELs

Acute REL (μg/m3): 20000
Species: Human
Acute REL Toxicologic Endpoint: Nervous system, respiratory system, eyes
Acute REL Target Organs: Nervous system, respiratory system, eyes
Severity: Mild
Last Acute REL Revision: 1999
Acute Reference Exposure Levels Comments:

OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D2.

Chronic REL

Chronic Inhalation REL (μg/m3): 35
Chronic Target Organs: Alimentary system (liver), kidney
Human Data: No
Last Chronic REL Revision: 1991
Chronic Reference Exposure Levels Comments:

ARB 2010. Toxic Air Contaminant Identification Reports

Proposition 65

Chemical Status

Cancer: Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Safe Harbor Levels

No Significant Risk Level (NSRL)
14 µg/day
Cancer

Water

California Public Health Goals Data

Health Risk Category: Carcinogenicity
Public Health Goal (mg/L): 0.00006
Public Health Goal - Download: pceaug2001.pdf
Cancer Risk at PHG: 0.000001
MCL value (mg/L): 0.005
Cancer Risk at MCL: 0.00008
Last PHG Revision : 2001
California PHG Comments: OEHHA 2013. Health Risk Information for Public Health Goal Exceedance Reports