Methylene Chloride (Dichloromethane)
CAS Number
75-09-2Synonym
Dichloromethane; DCM; Methylenum chloratum; NCI-C50102
Occurrence/Use
Solvent; paint stripper, degreaser; extraction agent for flavorings and to decaffeinate coffee and tea; aerosol propellant and blowing agent for polyurethane foams; manufacture of pharmaceuticals, film coatings, and electronics
Cancer Potency Information
| Latest Criteria: | California Public Health Goals |
|---|---|
| Inhalation Unit Risk (μg/cubic meter)-1: | 1.0 E-6 |
| Inhalation Slope Factor (mg/kg-day)-1: | 3.5 E-3 |
| Oral Slope Factor (mg/kg-day)-1: | 1.4 E-2 |
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. Listed as Methylene Chloride.
CDHS 1990. Risk Specific Intake Level for Methylene Chloride.
US EPA 1985. Updated Carcinogenicity Assessment of Dichloromethane (Methylene Chloride). |
Air
Acute RELs
| Acute REL (μg/m3): | 14000 |
|---|---|
| Species: | Human |
| Acute REL Toxicologic Endpoint: | Impairment of nervous system, increased blood carboxyhemoglobin |
| Acute REL Target Organs: | Cardiovascular system, nervous system |
| Severity: | Mild |
| Last Acute REL Revision: | 1999 |
| Acute Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D2. |
Chronic REL
| Chronic Inhalation REL (μg/m3): | 400 |
|---|---|
| Chronic Target Organs: | Cardiovascular system, nervous system |
| Human Data: | Yes |
| Last Chronic REL Revision: | 2000 |
| Chronic Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3
|
Proposition 65
Chemical Status
| Cancer: | Currently listed |
|---|
Cancer
| Listed as causing : | Listed as causing: Cancer |
|---|---|
| Date of Listing: |
Safe Harbor Levels
| Cancer |
Public notices related to this chemical
Water
California Public Health Goals Data
| Health Risk Category: | Carcinogenicity |
|---|---|
| Public Health Goal (mg/L): | 0.004 |
| Public Health Goal - Download: | dcm.pdf |
| Cancer Risk at PHG: | 0.000001 |
| MCL value (mg/L): | 0.005 |
| Cancer Risk at MCL: | 0.000001 |
| Last PHG Revision : | 09/08/2000 |
| California PHG Comments: | OEHHA 2013. Health Risk Information for Public Health Goal Exceedance Reports |