Hexamethylene Diisocyanate (Monomer)

CAS Number

822-06-0

Synonym

1,6-Diisocyanatohexane, 1,6-hexane diisocyanate, HMDI

HDI Monomer

Acute RELs

Acute REL (μg/m3): 
0.3
Species: 
Rodents
Acute REL Toxicologic Endpoint: 
Nasal epithelium lesions
Acute REL Target Organs: 
Respiratory system
Last Acute REL Revision: 
09/06/2019
Acute Reference Exposure Levels Comments: 

8-Hour RELs

8-Hour Inhalation REL (μg/m3): 
0.06
Last 8-Hour REL Revision: 
09/06/2019
8-Hour Reference Exposure Levels Comments: 

Chronic REL

Chronic Inhalation REL (μg/m3): 
0.03
Chronic Target Organs: 
Respiratory system
Human Data: 
Yes
Chronic Toxicologic Endpoint: 
HDI-induced asthma; accelerated decline in lung function
Last Chronic REL Revision: 
09/06/2019
Chronic Reference Exposure Levels Comments: