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Request for Relevant Information on the Carcinogenicity of Vinyl Acetate

Request for Information

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) has selected vinyl acetate for the Carcinogen Identification Committee (CIC)’s review for possible listing under the Safe Drinking Water and Toxic Enforcement Act of 1986, codified at Health and Safety Code [HSC] section 25249.5 et seq. (Proposition 65). This notice announces a data call-in to solicit information from the public relevant to the assessment of the carcinogenicity of the chemical. Vinyl acetate was selected from chemicals prioritized by the CIC in 2016. See the 2016 CIC Meeting Synopsis for more information.
Relevant information on vinyl acetate includes but is not limited to:

  • Cancer bioassays 
  • Cancer epidemiological studies 
  • Studies related to cancer mechanisms and the key characteristics of carcinogens 
  • Other pertinent studies on:
    • Pharmacokinetics 
    • Effects on biochemical and physiological processes, including findings in humans

Interested parties wishing to provide such information should submit it in accordance with the instructions given below.

At the request of the Vinyl Acetate Council, OEHHA hereby extends the data call-in period. The data call-in period will now close on Monday, September 18, 2023. The information received during this period will be reviewed and considered by OEHHA as it prepares the cancer hazard identification materials on vinyl acetate.

Background

OEHHA is the lead agency for the implementation of Proposition 65. The CIC of OEHHA’s Science Advisory Board serves as the state’s qualified experts and renders an opinion about whether a chemical has been clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer. (HSC section 25249.8(b); Title 27, California Code of Regulations, sections 25302, et seq., 25305(a)(1).) Chemicals identified as carcinogens by the CIC are added to the Proposition 65 list.  
Hazard identification materials will be made available to the public for comment prior to the CIC’s consideration of the chemical for possible listing. The availability of hazard identification materials will be announced in the California Regulatory Notice Register and on OEHHA’s website. 

Submission of Relevant Information

All written submissions must be provided to OEHHA by electronic submission, mail, or hand-delivery, by September 18, 2023. OEHHA strongly recommends that submissions be made electronically through our website at https://oehha.ca.gov/comments, rather than in paper form. Alternatively, the submission can be in paper form, either by mail or delivered in person. 

Electronic Submission (preferred):

Through OEHHA website at: https://oehha.ca.gov/comments

Mailed Submission:

Attention: Kiana Vaghefi
Office of Environmental Health Hazard Assessment
P. O. Box 4010
Sacramento, California 95812-4010

In-person delivery submission:

Attention: Kiana Vaghefi
Office of Environmental Health Hazard Assessment
1001 I Street, 23rd Floor
Sacramento, California 95814

OEHHA encourages all submissions to be in a format compliant with Section 508 of the federal Rehabilitation Act, Web Content Accessibility Guidelines (WCAG) 2.1 (see the World Wide Web Consortium [W3C] WCAG 2 Overview), and California Government Code sections 7405 and 11135, so that they can be read using screen reader technology.
OEHHA is subject to the California Public Records Act and other laws that require the release of certain information upon request. If you provide a submission, please be aware that your name, address and e-mail may be available to third parties.

If you have any questions, please contact Kiana Vaghefi at Kiana.Vaghefi@oehha.ca.gov or at (279) 216-0002.

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