Request for Information on Chemicals to be Considered by the OEHHA Science Advisory Board’s CIC

Request for Information on Chemicals to be Considered by the OEHHA Science Advisory Board’s Carcinogen Identification Committee

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65; Health and Safety Code Section 25249.5 et seq.).

The Carcinogen Identification Committee of OEHHA’s Science Advisory Board identifies chemicals for addition to the list of chemicals known to the State to cause cancer, which pursuant to Proposition 65 must be updated annually. The Committee serves as the State’s qualified experts for rendering an opinion whether a chemical has been clearly shown through scientifically valid testing according to generally accepted principles to cause cancer.

OEHHA has developed a procedure for prioritizing candidate chemicals for consideration under Proposition 65 by the State’s qualified experts. The process is described in “Procedure for Prioritizing Candidate Chemicals for Consideration Under Proposition 65 by the State’s Qualified Experts,” May 1997, and is available on the Internet at www.oehha.ca.gov. On October 17, 2003, OEHHA released for public comment draft priority assignments and draft data summaries for 47 “Batch #4” chemicals with respect to their potential to cause cancer. Today OEHHA announced the final priority assignments for 45 of these chemicals in a separate notice published elsewhere in this issue of the California Regulatory Notice Register.

In accordance with OEHHA’s prioritization procedure, all chemicals with final priority assignments of “high” carcinogenicity concern are placed on the final Candidate List, which is available on the OEHHA website (www.oehha.ca.gov). Chemicals are then selected from the Candidate List for the development of draft cancer hazard identification documents and subsequent consideration for listing by the Carcinogen Identification Committee of OEHHA’s Science Advisory Board.

The table below lists the chemicals added today to the candidate list, along with level of exposure concern.

TABLE 1. March 2004 Additions to the Candidate List

Consistent with OEHHA’s current (May 1997) prioritization procedure, chemicals with the highest level of exposure concern will be selected first from the Candidate List. At this time, therefore, OEHHA requests information relevant to the assessment of the evidence of carcinogenicity on the chemicals with high exposure concern listed in the table below.

TABLE 2. Chemicals for which OEHHA requests information relevant to carcinogenicity assessment

Interested parties or members of the public wishing to provide information relevant to the assessment of carcinogenicity for any of these chemicals should forward such information including, but not limited to, cancer bioassays, cancer epidemiological studies, genotoxicity testing, and other pertinent data on pharmacokinetics, biomarkers, and effects on biochemical and physiological processes in humans, to the address given below. The publication of this notice marks the start of a 60-day data call-in period. This period will end on Tuesday, May 11, 2004. The information received during this data call-in period will be reviewed and considered by OEHHA as it develops the draft cancer hazard identification documents on these compounds.

Notification of the availability of the hazard identification documents and of the time, date, location, and agenda of the meeting(s) of the Carcinogen Identification Committee where these chemicals will be considered will be provided in subsequent notices published in the California Regulatory Notice Register and posted on the Internet at the same web site address. It is anticipated that the draft hazard identification documents will be made available for a 60-day comment period prior to the Committee meetings at which these chemicals will be considered.

Relevant information on these chemicals should be sent in triplicate by mail or fax to:

Cynthia Oshita 
Office of Environmental Health Hazard Assessment
P.O. Box 4010
1001 I Steet
Sacramento , California 95812-4010
FAX: (916) 323-8803
Telephone: (916) 445-6900

Relevant information may also be delivered in person or by courier to the above address. It is requested, but not required, that written comments and supporting documentation be transmitted via email addressed to: coshita@oehha.ca.gov. In order to be considered, the relevant information must be postmarked (if sent by mail) or received at OEHHA (if hand-delivered, sent by FAX, or transmitted electronically) by 5:00 p.m. on Tuesday, May 11, 2004.

Downloads

Request for Information - 24 Chemicals March 12, 2004
Mar 12, 2004

Candidate List of Chemicals for Consideration by the Carcinogen Identification Committee March, 2004
Mar 12, 2004

Related Notices

• Procedure for Prioritizing Candidate Chemicals for Consideration Under Proposition 65 by the "State's Qualified Experts"
• Availability of Final Data Summaries and Priorities for Chemicals with Respect to Their Evaluation by the OEHHA Science Advisory Board’s CIC

  Mar 12, 2004
• Availability of Draft Data Summaries and Draft Priorities For 50 Chemicals With Respect to Their Potential to Cause Cancer: Request for Relevant Information

  Oct 17, 2003
• Availability of Hazard Identification Materials for 1,2,4-Trichlorobenzene and Announcement of the Carcinogen Identification Committee Meeting

  May 13, 2005
• Availability of Final Hazard Identification Document for 1,2,4-Trichlorobenzene

  Sep 1, 2005