Request for Information on Chemicals to be Considered by the Developmental and Reproductive Toxicant (DART) Identification Committee

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).

The Developmental and Reproductive Toxicant (DART) Identification Committee of OEHHA’s Science Advisory Board advises and assists OEHHA in compiling the list of chemicals known to the State to cause reproductive toxicity which is mandated by Health and Safety Code Section 25249.8. The Committee serve as the State’s qualified experts for rendering an opinion as to whether a chemical has been clearly shown through scientifically valid testing according to generally accepted principles to cause reproductive toxicity.

In accordance with the OEHHA’s process for preparing information on candidate chemicals for review by the State’s qualified experts, OEHHA will review the available reproductive toxicity literature and data on Carbamazepine and Progesterone, and prepare a summary of the information. The DART Identification Committee will consider the OEHHA summary of reproductive toxicity information before making recommendations regarding the reproductive and developmental toxicity of Carbamazepine and Progesterone. Interested parties or members of the public wishing to provide information relevant to an assessment of the reproductive and developmental toxicity of Carbamazepine or Progesterone should forward such information to the address given below. The publication of this notice marks the start of a 60-day data call-in period. This period ends on February 24, 1998. The information received during this data call-in period will be reviewed and considered by OEHHA as it develops the draft reproductive and developmental toxicity hazard identification documents on Carbamazepine and Progesterone.

OEHHA welcomes public participation and public input as part of these scientific assessments. If there is sufficient public interest, a public workshop or other public forum will be held to encourage scientific dialogue prior to completion of the draft hazard identification documents.

Notification of the availability of the draft hazard identification documents and of the time, date, location, and agenda of any workshops and of the meeting of the DART Identification Committee where Carbamazepine and Progesterone will be discussed will be provided in future notices published in the California Regulatory Notice Register and posted on OEHHA’s Home Page. It is anticipated that the draft hazard identification documents will be made available for a 60-day public comment period prior to the committee meeting at which Carbamazepine and Progesterone will be considered.

Relevant information on Carbamazepine and Progesterone should be sent in triplicate by mail or fax to:

Office of Environmental Health Hazard Assessment
P.O. Box 4010, MS-19B
Sacramento, California 95812-4010
Fax: (916) 323-2265

Street Address:

1001 I Street
Sacramento, California 95814

Relevant information may also be delivered in person or by courier to the above address.

In order to be considered, the relevant information must be postmarked (if sent by mail) or received at OEHHA (if hand-delivered or sent by fax) by 5:00 PM on February 24, 1998.