Request for Information, Availability of Draft Data Summaries and Draft Priorities for Chemicals with Respect to Their Potential to Cause Cancer

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA), as lead agency for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65), has developed a procedure for prioritizing chemicals for consideration under Proposition 65 by the "State’s qualified experts". Two committees of the Science Advisory Board (SAB), known as the Carcinogen Identification Committee, and the Developmental and Reproductive Toxicant (DART) Identification Committee, serve as the State’s qualified experts for rendering an opinion as to whether a chemical is known to the

 The procedure used by OEHHA to identify, prioritize and select candidate chemicals for evaluation by the SAB Committees is described in, "Procedure for Prioritizing Candidate Chemicals for Consideration Under Proposition 65 by the State’s Qualified Experts," May 1997. This procedure ensures that chemicals posing the highest level of cancer, birth defects or reproductive hazard concern are addressed first and forthwith by the SAB. In accordance with the prioritization procedure, we are announcing the release of the draft data summaries and draft priorities concerning the potential for the chemicals indicated below to cause cancer. This notice initiates a 60-day public comment period. The chemicals are:

Chemical

CASRN

Draft Level Of Carcinogenicity Concern

acronycine 7008-42-6 high
2-aminofluorene 153-78-6 high
2-amino-5-(5-nitro-2-furyl)
-1,3,4-oxadiazole
3775-55-1 high
4-amino-2-nitrophenol 119-34-6 high
N-butyl-N-nitrosourea 869-01-2 high
bis(2-chloro-1-methylethyl)ether 108-60-1 high
2,5-dimethoxy-4’-aminostilbene 23435-31-6 high
estragole 140-67-0 high
N-ethyl-N-formylhydrazine 74920-78-8 high
furfural 98-01-1 high
p-chloronitrobenzene 100-00-5 high
trichloroacetic acid 76-03-9 high
2-biphenylamine
(and strong acid salts)
2185-92-4 medium high
bromoethane 74-96-4 medium high
chlorthal-dimethyl 1861-32-1 medium high
cyanazine 21725-46-2 medium high
2,4-dichlorophenoxyacetic acid
and its salts and esters
94-75-7 medium high
dapsone 80-08-0 medium high
dimethyl hydrogen phosphite 868-85-9 medium-high
malonaldehyde and its salts 24382-04-5 medium high
b -thioguanine deoxyriboside 789-61-7 medium high
zearalenone 17924-92-4 medium high
bis(tri-n-butyltin)oxide 56-35-9 medium
dicofol 115-32-2 medium
di(2-ethylhexyl)adipate 103-23-1 medium
patulin 149-29-1 medium
pentachloronitrobenzene 82-68-8 medium
piperonyl sulfoxide 120-62-7 medium
Postponed   Status
salicylazosulfapyridine a 599-79-1 Authoritative body finding under evaluation by OEHHA
C.I. solvent yellow 14 (Sudan 1) a 842-07-9 Authoritative body finding under evaluation by OEHHA

CASRN = Chemical Abstracts Service Registration Number

a Under evaluation to determine whether the chemical meets the criteria for the authoritative bodies mechanism in 22 CCR Section 12306. If a chemical does not meet these criteria, it will be prioritized with the next batch of randomly selected chemicals.

OEHHA also announces that a public workshop to receive external scientific peer review and public comments on the draft data summaries and draft priority assignments for these chemicals will be held on Tuesday, November 18, 1997. The workshop will commence at 10:00 a.m. in the Auditorium at 744 P Street, Sacramento, California, and will last until all business has been conducted or until 5:00 p.m.

 OEHHA is committed to public participation and external scientific peer review in its implementation of Proposition 65, and welcomes public input. As part of its efforts to ensure that regulatory decisions are based upon a thorough consideration of all relevant information, OEHHA is soliciting information, scientific data and scientific peer review which may be relevant to the procedure for prioritizing these chemicals (see above) within the context of Proposition 65. The draft data summaries and draft priority assignments for these chemicals are available from the Proposition 65 Implementation Office at the address and telephone number indicated below, or in the downloads section below.

Written comments may be submitted to:

 the Proposition 65 Office
Office of Environmental Health Hazard Assessment
Post Office Box 4010
Sacramento, CA 95812-4010
FAX (916) 327-1097
(916) 445-6900

In order to be considered, comments must be postmarked (if sent by mail) or received at OEHHA (if delivered in person or sent by fax) by 5 p.m. Monday, December 1, 1997.