Notice to Change the Basis for Listing for Chloroform as Known to the State of California to Cause Reproductive Toxicity

Effective December 23, 2016, the basis for the listing of chloroform under Proposition 65[1] as known to cause reproductive toxicity is the state’s qualified experts mechanism.  This chemical was originally added in 2009 to the Proposition 65 list as causing reproductive toxicity via the “Labor Code mechanism” pursuant to Labor Code section 6382(d), which is incorporated by reference in Health and Safety Code section 25249.8(a).  Based on changes to certain federal regulations that affected the basis for the original listing of this chemical as causing reproductive toxicity, the California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) referred the chemical to the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for reconsideration.  In its official capacity as the “state’s qualified experts” at a public meeting held on October 27, 2016, the DARTIC determined that chloroform  has been clearly shown, through scientifically valid testing according to generally accepted principles, to cause reproductive toxicity and should remain on the Proposition 65 list.  Regulations governing the listing of chemicals by the DARTIC are set out in Title 27, California Code of Regulations, section 25305(b)(1).

The effective date of the listing of chloroform as known to cause reproductive toxicity remains unchanged:  August 7, 2009.

In summary, the chemical in the table below is being retained on the Proposition 65 list as known to the state to cause reproductive toxicity.

 

Chemical

CAS No.

Toxicological Endpoints

Listing Mechanism1

Chloroform

67-66-3

Developmental

SQE

1SQE: State’s Qualified Experts

Footnotes and References

[1] The Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as Proposition 65, is codified in Health and Safety Code section 25249.5 et seq.