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Chemical Listed Effective October 5, 2005 as Known to the State of California to Cause Cancer: Nitrapyrin

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is adding nitrapyrin to the list of chemicals known to the state to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Health and Safety Code section 25249.5 et seq., Proposition 65). The listing of the chemical is effective October 5, 2005.

Nitrapyrin (CAS No. 1929-82-4) is listed as a chemical known to the State of California to cause cancer. The listing of this chemical is based on a formal identification by an authoritative body (i.e., the U.S. Environmental Protection Agency (“U.S. EPA”)) that the chemical causes cancer. Regulations governing the listing of chemicals under the “authoritative bodies” mechanism are published in Title 22, Cal. Code of Regs. Section 12306.

The reader is directed to the Notice of Intent to List nitrapyrin published in the August 5, 2005, issue of the California Regulatory Notice Register (Register No. 2005, No. 31-Z) for the documentation supporting OEHHA’s determination that the criteria for administrative listing have been satisfied for this chemical. The documentation was developed to explain the basis for listing this chemical via the authoritative bodies provision of Proposition 65. OEHHA analyses of dose-response data to establish the no significant risk level (NSRL) for this chemical under Proposition 65 have not been conducted. The priority status of the development of an NSRL for nitrapyrin will be announced in a future OEHHA Proposition 65 Status Report for Safe Harbor Levels, available at /proposition-65.

A complete, updated Proposition 65 list is published elsewhere in this issue of the California Regulatory Notice Register. The following table outlines the addition of nitrapyrin to the Proposition 65 chemical list as known to the State to cause cancer:

Chemical CAS No. Toxicological
Endpoint		 Listing Mechanism
Nitrapyrin 1929-82-4 cancer AB

Listing mechanism:

AB – “authoritative bodies” mechanism (Title 22, Cal. Code of Regs. Section 12306)

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