Chemical Listed Effective July 29, 2011 as Known to the State of California to Cause Reproductive Toxicity: Sulfur Dioxide

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Effective July 29, 2011, the Office of Environmental Health Hazard Assessment (OEHHA) is adding sulfur dioxide (CAS No. 7446-09-5) to the list of chemicals known to the State to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 651).

Sulfur dioxide was considered by the Developmental and Reproductive Toxicant Identification Committee (DARTIC) in its official capacity as the “state’s qualified experts” at a public meeting held on July 12 and 13, 2011.  The DARTIC determined that sulfur dioxidewas clearly shown, through scientifically valid testing according to generally accepted principles, to cause developmental toxicity, an endpoint of reproductive toxicity.  Regulations governing the criteria for listing of chemicals by the DARTIC are set out in Title 27, California Code of Regulations, section 25305(b)(1). 

A complete, updated chemical list is published in this issue of the California Regulatory Notice Register and is available on the OEHHA website at

In summary, the following chemical is being listed under Proposition 65 as known to the State to cause reproductive toxicity:



Toxicological Endpoints

Listing Mechanism2

Sulfur dioxide 7446-09-5 Developmental toxicity SQE


Footnotes and References

1 Health and Safety Code section 25249.5 et seq.

2Listing mechanism:
SQE – “state’s qualified experts” mechanism (Title 27 Cal. Code of Regs., section 25305(b)(1)).