Chemical Listed Effective December 7, 2004 as Known to the State of California to Cause Reproductive Toxicity: 1-Bromopropane (1-BP)
The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is adding 1-bromopropane (1-BP) to the list of chemicals known to the state to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Health and Safety Code section 25249.5 et seq., Proposition 65). The listing of the chemical is effective December 7, 2004.
1-Bromopropane (1-BP) (CAS No. 106-94-5) is listed as a chemical known to the State of California to cause reproductive toxicity for the developmental, female and male reproductive endpoints. The listing of this chemical is based on a formal identification by an authoritative body (i.e., the National Toxicology Program [“NTP”]) that the chemical causes developmental, female and male reproductive toxicity. Regulations governing the listing of chemicals under the “authoritative bodies” mechanism are published in Title 22, Cal. Code of Regs. section 12306.
The reader is directed to the Notice of Intent to List 1-bromopropane (1-BP) published in the October 8, 2004, issue of the California Regulatory Notice Register (Register No. 2004, No. 41-Z) for the documentation supporting OEHHA's determination that the criteria for administrative listing have been satisfied for this chemical. The documentation was developed to explain the basis for listing this chemical via the authoritative bodies provision of Proposition 65. OEHHA analyses of dose-response data to establish the no significant risk level (NSRL) for this chemical under Proposition 65 have not been conducted. The priority status of the development of such analyses will be announced in a future OEHHA Proposition 65 Status Report for Safe Harbor Levels, available at /proposition-65.
A complete, updated Proposition 65 list is published elsewhere in this issue of the California Regulatory Notice Register. The following table outlines the addition of 1-bromopropane to the Proposition 65 chemical list as known to the State to cause reproductive toxicity:
Reproductive Toxicity
| Chemical | CAS No | Toxicological Endpoint | Listing Mechanism |
|---|---|---|---|
| 1-Bromopropane (1-BP) | 106-94-5 | Developmental, female reproductive and male reproductive toxicity | AB |
Listing mechanism:
AB – “authoritative bodies” mechanism (Title 22, Cal. Code of Regs. section 12306)
- 1-Bromopropane (1-BP)