CAS Number Correction to the Listing of the Chemical Doxorubicin Hydrochloride Known to the State to Cause Cancer And Reproductive Toxicity

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is making a correction to the listings of the chemical doxorubicin hydrochloride (Adriamycin) (CAS No. 23214-92-8).

Doxorubicin hydrochloride (Adriamycin) was listed as a chemical known to cause cancer on July 1, 1987. It was also listed as known to cause developmental and male reproductive toxicity on January 29, 1999. It was recently brought to the attention of OEHHA that the chemical was listed with the wrong Chemical Abstract Service (CAS) number, (CAS No. 23214-92-8) for each endpoint, cancer and reproductive toxicity. Accordingly, OEHHA revises both listings of the chemical, doxorubicin hydrochloride (Adriamycin), as known to cause cancer and known to cause developmental and male reproductive toxicity, with the correct CAS number, which is 25316-40-9. The effective dates of the chemical listings under the two endpoints remain the same.

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Cancer

Chemical CAS # Toxicological Endpoint Date of Listing
Doxorubicin hydrochloride (Adriamycin) 25316-40-9 cancer July 1, 1987


Reproductive toxicity

Chemical CAS # Toxicological Endpoint Date of Listing
Doxorubicin hydrochloride (Adriamycin) 25316-40-9 developmental
male reproductive
January 29, 1999