Announcement of the Developmental and Reproductive Toxicant Identification Committee Meeting Scheduled for December 14, 2021; Notice of Availability of Hazard Identification Materials for Perfluorononanoic Acid and Perfluorodecanoic Acid and Their Salts
November 5, 2021 update: One Additional Study Included in a revised Table 4.1 in the Hazard Identification Document for the December 14, 2021 Developmental and Reproductive Toxicant Identification Committee Meeting
Table 4.1 in the hazard identification document entitled "Evidence on the Male Reproductive Toxicity of Perfluorononanoic Acid (PFNA) and Its Salts and Perfluorodecanoic Acid (PFDA) and Its Salts" has been revised to include an additional study. Specifically, revised Table 4.1 PFNA: Epidemiologic studies of male reproductive toxicity has been updated to include an entry for the study by Lopez-Espinosa et al. (2016) on page 25 of this revised Table. The text of the hazard identification document released on October 1, 2021 has not been updated to include discussion of Lopez-Espinosa et al. (2016).
The full citation of the added study is: Lopez-Espinosa MJ, Mondal D, Armstrong BG, Eskenazi B, Fletcher T. 2016. Perfluoroalkyl substances, sex hormones, and insulin-like growth factor-1 at 6-9 years of age: A cross-sectional analysis within the C8 health project. Environ Health Perspect 124:1269-1275.
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) will convene a meeting of the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for possible listing of perfluorononanoic acid (PFNA) and its salts, and perfluorodecanoic acid (PFDA) and its salts, under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65)[1]. OEHHA is also opening a 45-day public comment period on the hazard identification document for these chemicals. The public comment period will end on Monday, November 15, 2021. A copy of the document is available on OEHHA’s web site at https://oehha.ca.gov/proposition-65. The document may also be requested from OEHHA’s Proposition 65 Implementation Office by calling (916) 445-6900.
Background
OEHHA is the lead agency for implementation of Proposition 65. The DARTIC advises and assists OEHHA in compiling the list of chemicals known to the state to cause reproductive toxicity as required by Proposition 65 [2]. The DARTIC serves as the state’s qualified experts for determining whether a chemical has been clearly shown through scientifically valid testing according to generally accepted principles to cause reproductive toxicity.
A request for relevant information on the potential reproductive toxicity of several chemicals, including PFNA and its salts and PFDA and its salts, opened on March 26, 2021 and closed on May 10, 2021. No submissions were received on PFNA and its salts or on PFDA and its salts.
Public Meeting and Public Comment Period
PFNA and its salts and PFDA and its salts will be considered for possible listing under Proposition 65 as causing reproductive toxicity (male reproductive endpoint) at a public meeting scheduled for Tuesday, December 14, 2021. The meeting, which will be held virtually, will begin at 10:00 a.m. and last until all business is conducted or until 5:00 p.m. The agenda for the meeting and instructions on how to participate will be provided in a future public notice published in advance of the meeting.
The public may provide oral comments at the meeting on December 14, 2021. These comments will be limited to five minutes per commenter, except for those commenters who make a request by November 15, 2021, and receive approval from the Chair of the DARTIC for longer comments. Please submit a request for additional time, with an estimate of the time you will need and the reason you are requesting additional time, to P65Public.Comments@oehha.ca.gov or call the Proposition 65 Implementation Office at (916) 445‑6900 by November 15, 2021.
OEHHA must receive written comments no later than November 15, 2021, the designated close of the written comment period, and strongly recommends that information be submitted electronically, rather than in paper form. Comments may be submitted electronically through our website at https://oehha.ca.gov/comments. All timely filed public comments will be provided to DARTIC members in advance of the meeting and will be posted on the OEHHA website at the close of the comment period. Comments submitted in paper form can be mailed or delivered in person to the address below.
All non-electronic submissions should be directed to:
Tyler Saechao
Office of Environmental Health Hazard Assessment
1001 I Street
P. O. Box 4010, MS-12B
Sacramento, California 95812-4010
Telephone: 916-445-6900
OEHHA is subject to the California Public Records Act and other laws that require the release of certain information upon request. If you provide comments, please be aware that your name, address, and e-mail may be available to third parties.
If you have any questions, please contact Tyler Saechao at Tyler.Saechao@OEHHA.ca.gov or (916) 445-6900.
- Perfluorononanoic acid (PFNA) and its salts
- Perfluorodecanoic Acid (PFDA) and Its Salts
Chemical Reference
Footnotes and References
[1] Health and Safety Code section 25249.5 et seq.
[2] Health and Safety Code section 25249.8