Notice of Intent to List Chemicals: Benthiavalicarb-isopropyl, Mepanipyrim, Pirimicarb and Resmethrin

The Safe Drinking Water and Toxic Enforcement Act of 1986 (commonly known as Proposition 65), codified at Health and Safety Code section 25249.5 et seq., provides two primary mechanisms for administratively listing chemicals that are known to the State to cause cancer or reproductive toxicity (Health and Safety Code section 25249.8(b)).  A chemical may be listed under Proposition 65 when a body considered to be authoritative by the state’s qualified experts has formally identified the chemical as causing cancer or reproductive toxicity.  The following entities are identified as authoritative bodies for purposes of Proposition 65, as it pertains to chemicals known to cause cancer:  the U.S. Environmental Protection Agency, the International Agency for Research on Cancer, the U.S. Food and Drug Administration, the National Institute for Occupational Safety and Health, and the National Toxicology Program.  The criteria for listing chemicals through the authoritative bodies mechanism are set forth in Title 22, California Code of Regulations, section 12306.

As the lead agency for the implementation of Proposition 65, the Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency intends to list the chemicals identified in the table below as known to the State to cause cancer, pursuant to this administrative mechanism as provided in Health and Safety Code section 25249.8(b) and Title 22, Cal. Code of Regs., section 12306.

Relevant information related to the possible listing of the identified chemicals was requested in a notice published in the California Regulatory Notice Register on February 15, 2008 (Register 2008, No. 7-Z).  No public comments were received.  OEHHA has determined that benthiavalicarb-isopropyl, mepanipyrim, pirimicarb and resmethrin meet the criteria for listing under Title 22, Cal. Code of Regs., section 12306, and therefore OEHHA is issuing this notice of intent to list these chemicals under Proposition 65.  A document providing more detail on the basis for the listing of these chemicals can be obtained from OEHHA’s Proposition 65 Implementation Office at the address and telephone number indicated below, or from the OEHHA Web site. Anyone wishing to provide comments as to whether the listing of benthiavalicarb-isopropyl, mepanipyrim, pirimicarb or resmethrin meets the criteria for listing provided in Title 22, Cal. Code of Regs., section 12306 should send written comments in triplicate, along with any supporting documentation, by mail or by fax to:

Proposition 65
Office of Environmental Health Hazard Assessment
Street Address:  1001 I Street
Sacramento, California  95814

Mailing Address:  P.O. Box 4010
Sacramento, California  95812-4010

Fax No.:  (916) 323-8803
Telephone:  (916) 445-6900

Comments may also be delivered in person or by courier to the above address.  It is requested, but not required, that written comments and supporting documentation be transmitted via email addressed to:  P65Public.Comments@oehha.ca.gov.  In order to be considered, comments must be received at OEHHA by 5:00 p.m. on Monday, June 2, 2008.

The following chemicals have been determined by OEHHA to meet the criteria set forth in Title 22, Cal. Code of Regs., section 12306 for listing as causing cancer under the authoritative bodies mechanism:

Chemical

CAS No.

Reference

Benthiavalicarb-isopropyl1

177406-68-7

U.S. EPA,  (2005a)

Mepanipyrim1

110235-47-7

U.S. EPA, (2004)

Pirimicarb

23103-98-02

U.S. EPA, (2005b)

Resmethrin

10453-86-8

U.S. EPA, (2005c)

Footnotes and References

REFERENCES

U.S. Environmental Protection Agency (U.S. EPA, 2004).  Cancer Assessment Document.  Evaluation of the Carcinogenic Potential of Mepanipyrim.  Cancer Assessment Review Committee. Health Effects Division.  Office of Pesticide Programs. April 20, 2004.  

U.S. Environmental Protection Agency (U.S. EPA, 2005a).   Cancer Assessment Document.  Evaluation of the Carcinogenic Potential of Benthiavalicarb-isopropyl.  Cancer Assessment Review Committee, Health Effects Division, Office of Pesticide Programs.  October 18, 2005. 

U.S. Environmental Protection Agency (U.S. EPA, 2005b).  Cancer Assessment Document.  Evaluation of the Carcinogenic Potential of Pirimicarb.  Cancer Assessment Review Committee.  Health Effects Division.  Office of Pesticide Programs.  July 13, 2005.

U.S. Environmental Protection Agency (U.S. EPA, 2005c).   Cancer Assessment Document.   Evaluation of the Carcinogenic Potential of Resmethrin.  Cancer Assessment Review Committee, Health Effects Division, Office of Pesticide Programs. May 25, 2005. 

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FOOTNOTES

1 Not currently registered in the United States.