Di(2-ethylhexyl)phthalate (DEHP)

Chemical Status

Cancer:	Currently listed
Reproductive Toxicity:	Currently listed

Chemical Listing Details

Cancer

Listed as causing:	Listed as causing: Cancer
Date of Listing:	01/01/1988
Basis for Listing:	State's Qualified Experts

Reproductive Toxicity

Listed as causing:	Developmental Toxicity Male Reproductive Toxicity
Developmental Toxicity
Date of Listing:	10/24/2003
Basis for Listing:	Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration
Male Reproductive Toxicity
Date of Listing:	10/24/2003
Basis for Listing:	Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL):	310 (adult) µg/day
Reproductive Toxicity
Maximum Allowable Dose Level (MADL) :	4200 µg/day (intravenous- adult); 600 µg/day (intravenous- infant boys, age 29 days to 24 months); 210 µg/day (intravenous- neonatal infant boys, age 0 to 28 days)
Maximum Allowable Dose Level (MADL) - Oral:	410 µg/day (adult); 58 µg/day (infant boys, age 29 days to 24 months); 20 µg/day (neonatal infant boys, age 0 to 28 days)

Documents, Presentations, and Publications

Cancer:

No Significant Risk Level for Di(2-Ethylhexyl) Phthalate June 1, 2002

Reproductive Toxicity:

Maximum Allowable Dose Level for Di(2-Ethylhexyl) Phthalate by Intravenous Injection February 1, 2006 Maximum Allowable Dose Level for Di(2-Ethylhexyl) Phthalate by Oral Exposure June 24, 2005 Notice of Intent to List - di(2-ethylhexyl)phthalate April 11, 2003 Package 6d - Chemical Meeting the Criteria for Listing di(2-ethylhexyl)phthalate April 11, 2003 Listing Notice - Di(2-ethylhexyl)phthalate October 24, 2003

Public Notices Related to this Chemical

• Notice of Intent to List Chemical: di(2-ethylhexyl)phthalate
• Chemical Listed Effective October 24, 2003 as Known to the State to Cause Reproductive Toxicity: Di(2-ethylhexyl)phthalate (DEHP)
• Notice of Proposed Rulemaking, Amendment to Title 22, Section 12805, Specific Regulatory Levels for di(2-ethylhexyl)phthalate (DEHP)
• Notice of Proposed Rulemaking, MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Oral Exposure
• Notice of Addition of Documents and Information to Rulemaking File, OAL FILE No. Z-05-0614-06 Amendment to Section 12805, MADL for DEHP by Oral Exposure
• Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
• Correction to the Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
• Notice of Addition of Documents and Information to Rulemaking File, OAL FILE Z-01-1019-06, Amendment to 12805, MADL for DEHP by Intravenous Injection
• Notice of Addition of Documents and Information to Rulemaking File, OAL FILE 05-1027-05 S, Amendment to Section 12805, Maximum Allowable Dose Level (MADL) for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Intravenous Injection
• Notice of Adoption to Text of Regulations Title 22, California Code of Regulations Amendment to Section 12805 Maximum Allowable Dose Levels (MADLs) for Di(2-ethylhexyl)phthalate (by Intravenous Injection)