Di(2-ethylhexyl)phthalate
CAS Number
117-81-7Synonym
AI3-04273; BEHP; Bis(2-ehtylhexyl) phthalate; Di(2-ethylhexyl)phthalate; Diethylhexyl phthalate; DEHP; Ethylhexyl phthalate; NCI-C52733; Octyl phthalate; Vinicizer 80; EPA Pesticide Chemical Code: 295200
Occurrence/Use
Plasticizer for many resins and elastomers; component of tobacco smoke
| Inhalation Unit Risk (μg/cubic meter)-1: |
2.4 E-6
|
|---|---|
| Inhalation Slope Factor (mg/kg-day)-1: |
8.4 E-3
|
| Oral Slope Factor (mg/kg-day)-1: |
3.0 E-3
|
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.
OEHHA 1997. Public Health Goal for Di(2-ethylhexyl)phthalate (DEHP) in Drinking Water. |
Air
Use inhalation Unit Risk of 2.4E-6 and Inhalation/Oral cancer potency of 8.4E-3 based on the PHG values
Proposition 65
| Cancer: |
Currently listed
|
|---|---|
| Reproductive Toxicity: |
Currently listed
|
| Listed as causing: |
Cancer
|
|---|---|
| Date of Listing: |
01/01/1988
|
| Basis for Listing: |
State's Qualified Experts
|
| Listed as causing: |
Developmental Toxicity
Male Reproductive Toxicity
|
|---|---|
| Developmental Toxicity | |
| Date of Listing: |
10/24/2003
|
| Basis for Listing: |
Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration
|
| Male Reproductive Toxicity | |
| Date of Listing: |
10/24/2003
|
| Basis for Listing: |
Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration
|
| Cancer | |
| No Significant Risk Level (NSRL): |
310 (adult) µg/day
|
|---|---|
| Reproductive Toxicity | |
| Maximum Allowable Dose Level (MADL) : |
4200 µg/day (intravenous- adult); 600 µg/day (intravenous- infant boys, age 29 days to 24 months); 210 µg/day (intravenous- neonatal infant boys, age 0 to 28 days)
|
| Maximum Allowable Dose Level (MADL) - Oral: |
410 µg/day (adult); 58 µg/day (infant boys, age 29 days to 24 months); 20 µg/day (neonatal infant boys, age 0 to 28 days)
|
| Last NSRL/MADL Revision: |
2006
|
| Cancer: | |
|---|---|
| Reproductive Toxicity: |
Public notices related to this chemical:
- Notice of Intent to List Chemical: di(2-ethylhexyl)phthalate
- Chemical Listed Effective October 24, 2003 as Known to the State to Cause Reproductive Toxicity: Di(2-ethylhexyl)phthalate (DEHP)
- Notice of Proposed Rulemaking, Amendment to Title 22, Section 12805, Specific Regulatory Levels for di(2-ethylhexyl)phthalate (DEHP)
- Notice of Proposed Rulemaking, MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Oral Exposure
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE No. Z-05-0614-06 Amendment to Section 12805, MADL for DEHP by Oral Exposure
- Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
- Correction to the Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE Z-01-1019-06, Amendment to 12805, MADL for DEHP by Intravenous Injection
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE 05-1027-05 S, Amendment to Section 12805, Maximum Allowable Dose Level (MADL) for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Intravenous Injection
- Notice of Adoption to Text of Regulations Title 22, California Code of Regulations Amendment to Section 12805 Maximum Allowable Dose Levels (MADLs) for Di(2-ethylhexyl)phthalate (by Intravenous Injection)
Water
| Health Risk Category: |
Carcinogenicity
|
|---|---|
| Public Health Goal (mg/L): |
0.012
|
| Public Health Goal - Download: | |
| Cancer Risk at PHG: |
0.000001
|
| MCL value (mg/L): |
0.004
|
| Cancer Risk at MCL: |
0.0000003
|
| Last PHG Revision : |
1997
|
| California PHG Comments: |