Di(2-ethylhexyl)phthalate
CAS Number
117-81-7Synonym
AI3-04273; BEHP; Bis(2-ehtylhexyl) phthalate; Di(2-ethylhexyl)phthalate; Diethylhexyl phthalate; DEHP; Ethylhexyl phthalate; NCI-C52733; Octyl phthalate; Vinicizer 80; EPA Pesticide Chemical Code: 295200
Occurrence/Use
Plasticizer for many resins and elastomers; component of tobacco smoke
Cancer Potency Information
| Inhalation Unit Risk (μg/cubic meter)-1: | 2.4 E-6 |
|---|---|
| Inhalation Slope Factor (mg/kg-day)-1: | 8.4 E-3 |
| Oral Slope Factor (mg/kg-day)-1: | 3.0 E-3 |
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.
OEHHA 1997. Public Health Goal for Di(2-ethylhexyl)phthalate (DEHP) in Drinking Water. |
Air
Hot Spots Unit Risk and Cancer Potency values
Use inhalation Unit Risk of 2.4E-6 and Inhalation/Oral cancer potency of 8.4E-3 based on the PHG values
Proposition 65
MADL w/ File
Chemical Status
| Cancer: | Currently listed |
|---|---|
| Reproductive Toxicity : | Currently listed |
Cancer
| Listed as causing : | Listed as causing: Cancer |
|---|---|
| Date of Listing: |
Reproductive Toxicity
| Listed as causing: | Developmental Toxicity Male Reproductive Toxicity | Developmental Toxicity |
|---|---|
| Date of Listing: | |
| Basis for Listing : | Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration | Male Reproductive Toxicity |
| Date of Listing: | |
| Basis for Listing : | Authoritative Bodies-National Institute for Occupational Safety and Health/US Food and Drug Administration |
Safe Harbor Levels
| Cancer | |
| Reproductive Toxicity | |
| Maximum Allowable Dose Level (MADL) : | 4200 µg/day (intravenous- adult); 600 µg/day (intravenous- infant boys, age 29 days to 24 months); 210 µg/day (intravenous- neonatal infant boys, age 0 to 28 days) |
|---|---|
| Maximum Allowable Dose Level (MADL) - Oral: | 410 µg/day (adult); 58 µg/day (infant boys, age 29 days to 24 months); 20 µg/day (neonatal infant boys, age 0 to 28 days) |
| Last NSRL/MADL Revision: | 2006 |
Documents, Presentations, and Publications
| Cancer: |
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| Reproductive Toxicity: |
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Public notices related to this chemical
- Notice of Intent to List Chemical: di(2-ethylhexyl)phthalate
- Chemical Listed Effective October 24, 2003 as Known to the State to Cause Reproductive Toxicity: Di(2-ethylhexyl)phthalate (DEHP)
- Notice of Proposed Rulemaking, Amendment to Title 22, Section 12805, Specific Regulatory Levels for di(2-ethylhexyl)phthalate (DEHP)
- Notice of Proposed Rulemaking, MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Oral Exposure
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE No. Z-05-0614-06 Amendment to Section 12805, MADL for DEHP by Oral Exposure
- Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
- Correction to the Notice of Modifications to Text of Proposed Regulations Section 12805 (MADL for Reproductive Toxicity for Di(2-ethylhexyl)phthalate by Intravenous Injection)
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE Z-01-1019-06, Amendment to 12805, MADL for DEHP by Intravenous Injection
- Notice of Addition of Documents and Information to Rulemaking File, OAL FILE 05-1027-05 S, Amendment to Section 12805, Maximum Allowable Dose Level (MADL) for Reproductive Toxicity for Di(2-ethylhexyl)phthalate (DEHP) by Intravenous Injection
- Notice of Adoption to Text of Regulations Title 22, California Code of Regulations Amendment to Section 12805 Maximum Allowable Dose Levels (MADLs) for Di(2-ethylhexyl)phthalate (by Intravenous Injection)
Water
California Public Health Goals Data
| Health Risk Category: | Carcinogenicity |
|---|---|
| Public Health Goal (mg/L): | 0.012 |
| Public Health Goal - Download: | dehpc.pdf |
| Cancer Risk at PHG: | 0.000001 |
| MCL value (mg/L): | 0.004 |
| Cancer Risk at MCL: | 0.0000003 |
| Last PHG Revision : | 1997 |
| California PHG Comments: | OEHHA 2013. Health Risk Information for Public Health Goal Exceedance Reports |