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Tetrachloroethylene

CAS Number

127-18-4

Synonym

AI3-01860; Ankilostin; Antisal 1; Antisol 1; Caswell No. 827; Didakene; Ethylene Tetrachloride; NCI-C04580; Nema; PCE; Perchlor; Perchloroethylene; PERC; Perclene; Perklone; Tetracap; Tetrachloroethylene; Tetrachloroethene; Tetraleno; Tetralex; Tetropil; EPA Pesticide Code: 078501

Occurrence/Use

Solvent for organic materials used in dry-cleaning, textile processing, and vapor-degreasing; chemical intermediate. Formerly used in medicine as a hookworm vermifuge.

Tetrachloroethylene

Soil Screening

Last CHHSL revision: 
1/2005
CHHSL Comments: 

For chemical-specific screening levels for use in assessing contaminated sites, please see HHRA Note 3 (DTSC HERO). https://www.dtsc.ca.gov/assessingrisk/humanrisk2.cfm

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 
6.1 E-6
Inhalation Slope Factor (mg/kg-day)-1: 
2.1 E-2
Oral Slope Factor (mg/kg-day)-1: 
5.4 E-1
Last Cancer Potency Revision: 
09/08/2016
Comments/References: 

Listed as Perchloroethylene.

(OEHHA 2016) Notice of Adoption of Inhalation Cancer Unit Risk Factor for Perchloroethylene

(OEHHA 2016) Perchloroethylene Unit Risk Factor – Review Draft for Scientific Review Panel on Toxic Air Contaminants

(OEHHA 2009) Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

(OEHHA 2001) Public Health Goal for Tetrachloroethylene in Drinking Water.

(ARB/OEHHA 1991) Toxic Air Contaminant Identification Report: Perchloroethylene.

(OEHHA 1988) Proposition 65 NSRL is based on the human cancer potency value of 0.05 (mg/kg-day)-1

 

Air

Acute RELs

Acute REL (μg/m3): 
20000
Species: 
Human
Acute REL Toxicologic Endpoint: 
Nervous system, respiratory system, eyes
Acute REL Target Organs: 
Nervous system, respiratory system, eyes
Severity: 
Mild
Last Acute REL Revision: 
1999
Acute Reference Exposure Levels Comments: 

Chronic REL

Chronic Inhalation REL (μg/m3): 
35
Chronic Target Organs: 
Alimentary system (liver), kidney
Human Data: 
No
Last Chronic REL Revision: 
1991
Chronic Reference Exposure Levels Comments: 

Proposition 65

Chemical Status

Cancer: 
Currently listed

Cancer

Listed as causing: 
Cancer
Date of Listing: 
04/01/1988
Basis for Listing: 
State's Qualified Experts

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
14 µg/day

Water

California Public Health Goals Data

Health Risk Category: 
Carcinogenicity
Public Health Goal (mg/L): 
0.00006
Public Health Goal - Download: 
Cancer Risk at PHG: 
0.000001
MCL value (mg/L): 
0.005
Cancer Risk at MCL: 
0.00008
Last PHG Revision : 
2001
California PHG Comments: