1. Home
  2. Library
  3. Chemicals
  4. Toluene Diisocyanates (2,4 and 2, 6)

Toluene Diisocyanates (2,4 and 2, 6)

CAS Number

584-84-9; 91-08-7

Synonym

AI3-15101; 1,3-diisocyanato-2-methylbenzene; 1,3-diisocyanatomethyl benzene; 2,6-diisocyanatotoluene; Cresorcinol diisocyanate; desmodur T80; 2,4-diisocyanato-1-methylbenzene; 2,4- and 2,6-diisocyanatotoluene; Hylene T; Isocyanic Acid, methylphenylene ester; 4-methyl-m-phenylene isocyanate; 2-methyl-meta-phenylene isocyanate; Mondur TD; Nacconate 100; NCI-C50533; Niax TDI; Meta-toluene diisocyanate; Tolylene-2,4-diisocyanate; Tolylene diisocyanate; m-Tolylene diisocyanate; 2,4- and 2,6-TDI, 26471-62-5 (TDI mixture)

Occurrence/Use

Manufacture of flexible polyurethane foam, elastomers, wood finishes, lacquers, foam-coated fabrics, and insulation materials. Often available as a mixture of the two isomers, though 2,4-TDI is produced in its pure state.

Cancer Potency Information

Latest Criteria: 
Chronic Reference Exposure Levels
Inhalation Unit Risk (μg/cubic meter)-1: 
1.1 E-5
Inhalation Slope Factor (mg/kg-day)-1: 
3.9 E-2
Oral Slope Factor (mg/kg-day)-1: 
3.9 E-2
Comments/References: 

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Air

Acute RELs

Acute REL (μg/m3): 
2
Species: 
Human
Acute REL Target Organs: 
Respiratory system
Last Acute REL Revision: 
3/30/2016
Acute Reference Exposure Levels Comments: 

8-Hour RELs

8-Hour Inhalation REL (μg/m3): 
0.015
Last 8-Hour REL Revision: 
3/30/2016
8-Hour Reference Exposure Levels Comments: 

Chronic REL

Chronic Inhalation REL (μg/m3): 
0.008
Chronic Target Organs: 
Respiratory system
Human Data: 
yes
Last Chronic REL Revision: 
3/30/2016
Chronic Reference Exposure Levels Comments: