Toluene Diisocyanates (2,4 and 2, 6)
CAS Number
584-84-9; 91-08-7Synonym
AI3-15101; 1,3-diisocyanato-2-methylbenzene; 1,3-diisocyanatomethyl benzene; 2,6-diisocyanatotoluene; Cresorcinol diisocyanate; desmodur T80; 2,4-diisocyanato-1-methylbenzene; 2,4- and 2,6-diisocyanatotoluene; Hylene T; Isocyanic Acid, methylphenylene ester; 4-methyl-m-phenylene isocyanate; 2-methyl-meta-phenylene isocyanate; Mondur TD; Nacconate 100; NCI-C50533; Niax TDI; Meta-toluene diisocyanate; Tolylene-2,4-diisocyanate; Tolylene diisocyanate; m-Tolylene diisocyanate; 2,4- and 2,6-TDI, 26471-62-5 (TDI mixture)
Occurrence/Use
Manufacture of flexible polyurethane foam, elastomers, wood finishes, lacquers, foam-coated fabrics, and insulation materials. Often available as a mixture of the two isomers, though 2,4-TDI is produced in its pure state.
Cancer Potency Information
| Latest Criteria: | Chronic Reference Exposure Levels |
|---|---|
| Inhalation Unit Risk (μg/cubic meter)-1: | 1.1 E-5 |
| Inhalation Slope Factor (mg/kg-day)-1: | 3.9 E-2 |
| Oral Slope Factor (mg/kg-day)-1: | 3.9 E-2 |
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. |
Air
Acute RELs
| Acute REL (μg/m3): | 2 |
|---|---|
| Species: | Human |
| Acute REL Target Organs: | Respiratory system |
| Last Acute REL Revision: | 3/30/2016 |
| Acute Reference Exposure Levels Comments: |
8-Hour RELs
| 8-Hour Inhalation REL (μg/m3): | 0.015 |
|---|---|
| Last 8-Hour REL Revision: | 3/30/2016 |
| 8-Hour Reference Exposure Levels Comments: |
Chronic REL
| Chronic Inhalation REL (μg/m3): | 0.008 |
|---|---|
| Chronic Target Organs: | Respiratory system |
| Human Data: | yes |
| Last Chronic REL Revision: | 3/30/2016 |
| Chronic Reference Exposure Levels Comments: |
Reference Exposure Levels for Toluene Diisocyanate (TDI)
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