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Safrole

CAS Number

94-59-7

Synonym

Allylcatechol methylene ether; Allyldioxybenzene methylene ether; 1-allyl-3,4-methylenedioxybenzene; 4-Allyl-1,2-methylenedioxybenzene; allylpyrocatechol methylene ether; 1,2-methylenedioxy-4-allylbenzene; Rhyuno oil; Safrene; Safrol; Shikimol; Sassafras; EPA Pesticide Code: 097901

Occurrence/Use

Naturally occurring in small amounts in spices such as cinnamon, nutmeg, sassafras, and black pepper; principal component of brown camphor oil. Formerly used as fragrance and flavoring

Cancer Potency Information

Latest Criteria: 
Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 
6.3 E-5
Inhalation Slope Factor (mg/kg-day)-1: 
2.2 E-1
Oral Slope Factor (mg/kg-day)-1: 
2.2 E-1
Comments/References: 

Proposition 65

Chemical Status

Cancer: 
Currently listed

Cancer

Listed for: 
Cancer
Date of Listing: 
01/01/1988
Basis for Listing: 
State's Qualified Experts

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
3 µg/day
Last NSRL/MADL Revision: 
1992

Documents, Presentations, and Publications

Cancer: