Safrole

CAS Number

94-59-7

Synonym

Allylcatechol methylene ether; Allyldioxybenzene methylene ether; 1-allyl-3,4-methylenedioxybenzene; 4-Allyl-1,2-methylenedioxybenzene; allylpyrocatechol methylene ether; 1,2-methylenedioxy-4-allylbenzene; Rhyuno oil; Safrene; Safrol; Shikimol; Sassafras; EPA Pesticide Code: 097901

Occurrence/Use

Naturally occurring in small amounts in spices such as cinnamon, nutmeg, sassafras, and black pepper; principal component of brown camphor oil. Formerly used as fragrance and flavoring

Cancer Potency Information

Latest Criteria: Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 6.3 E-5
Inhalation Slope Factor (mg/kg-day)-1: 2.2 E-1
Oral Slope Factor (mg/kg-day)-1: 2.2 E-1
Comments/References:

OEHHA 1992. Expedited Cancer Potency Values and Proposed Regulatory Levels for Certain Proposition 65 Carcinogens.

Proposition 65

Chemical Status

Cancer: Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Safe Harbor Levels

No Significant Risk Level (NSRL)
3 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer: