Nickel Hydroxide

CAS Number

12054-48-7; 12125-56-3
Nickel Hydroxide

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 2.6 E-4
Inhalation Slope Factor (mg/kg-day)-1: 9.1 E-1
Oral Slope Factor (mg/kg-day)-1: 9.1 E-1
Comments/References:

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Listed as Nickel and nickel compounds.

Air

Acute RELs

Acute REL (μg/m3): 0.2
Species: Mouse
Acute REL Toxicologic Endpoint: Depressed antibody response
Acute REL Target Organs: Immune system
Last Acute REL Revision: 2012
Acute Reference Exposure Levels Comments:

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds.

8-Hour RELs

8-Hour Inhalation REL (μg/m3): 0.06
Last 8-Hour REL Revision: 2012
8-Hour Reference Exposure Levels Comments:

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. Listed as Nickel & nickel compounds.

Chronic REL

Chronic Inhalation REL (μg/m3): 0.014 (inhalation); 11 μg/kg BW-day (oral)
Chronic Target Organs: Inhalation: Respiratory system, hematologic system. Oral: Development
Human Data: No
Last Chronic REL Revision: 2012
Chronic Reference Exposure Levels Comments:

Inhalation concentrations as micrograms Ni/m3; oral dose as micrograms Ni/kg-day.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds (except nickel oxide for chronic inhalation exposures).

Proposition 65

Chemical Status

Cancer: Currently listed

Cancer

Cancer - Listing Mechanism
Labor Code
Listed as causing : Listed as causing: Cancer
Date of Listing:

Comments

Listed as Nickel hydroxide.

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