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Nickel Carbonyl

CAS Number

13463-39-3
Nickel Carbonyl

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 
2.6 E-4
Inhalation Slope Factor (mg/kg-day)-1: 
9.1 E-1
Oral Slope Factor (mg/kg-day)-1: 
9.1 E-1
Comments/References: 

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Listed as Nickel and nickel compounds.

Air

Acute RELs

Acute REL (μg/m3): 
0.2
Species: 
Mouse
Acute REL Toxicologic Endpoint: 
Depressed antibody response
Acute REL Target Organs: 
Immune system
Last Acute REL Revision: 
2012
Acute Reference Exposure Levels Comments: 

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds.

8-Hour RELs

8-Hour Inhalation REL (μg/m3): 
0.06
Last 8-Hour REL Revision: 
2012
8-Hour Reference Exposure Levels Comments: 

Inhalation concentrations as micrograms Ni/m3.
OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. Listed as Nickel & nickel compounds.

Chronic REL

Chronic Inhalation REL (μg/m3): 
0.014 (inhalation); 11 μg/kg BW-day (oral)
Chronic Target Organs: 
Inhalation: Respiratory system, hematologic system. Oral: Development
Human Data: 
No
Last Chronic REL Revision: 
2012
Chronic Reference Exposure Levels Comments: 

Inhalation concentrations as micrograms Ni/m3; oral dose as micrograms Ni/kg-day.
OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds (except nickel oxide for chronic inhalation exposures).

Proposition 65

Chemical Status

Cancer: 
Currently listed
Reproductive Toxicity: 
Currently listed

Cancer

Listed for: 
Cancer
Date of Listing: 
10/01/1987
Basis for Listing: 
State's Qualified Experts

Reproductive Toxicity

Listed for: 
Developmental Toxicity
Developmental Toxicity
Date of Listing: 
09/01/1996
Basis for Listing: 
Authoritative Bodies-US Environmental Protection Agency

Comments

Listed as Nickel carbonyl.

Public notices related to this chemical: 

Water

California Public Health Goals Data

Health Risk Category: 
Developmental toxicity (increased neonatal deaths)
Cancer Risk at PHG: 
n/a
MCL value (mg/L): 
0.1
Cancer Risk at MCL: 
n/a
Last PHG Revision : 
2001
California PHG Comments: 

Not considered an oral carcinogen; PHG based on reproductive toxicity. OEHHA 2001. Public Health Goal for Nickel. PHG applies to soluble nickel compounds.