n-Nitrosonornicotine

CAS Number

16543-55-8

Synonym

1'-dimethyl-1'-nitrosonicotine; 1'-nitroso-1'-demethylnicotine; Nitrosonornicotine; N'-nitrosonornicotine; 1'-nitrosonornicotine; 1-nitroso-2-(3-pyridyl)pyrroluidine; 3-(1-nitroso-2-pyrrolidinyl)pyridine; NNN

Occurrence/Use

Research chemical (induces cancer). Produced in curing, ageing, processing, and smoking of tobacco products; produced endogenously from nitrite in saliva and tobacco alkaloids including nicotine

n-Nitrosonornicotine

Cancer Potency Information

Latest Criteria: Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 4.0 E-4
Inhalation Slope Factor (mg/kg-day)-1: 1.4 E+0
Oral Slope Factor (mg/kg-day)-1: 1.4 E+0
Comments/References:

OEHHA 1992. Expedited Cancer Potency Values and Proposed Regulatory Levels for Certain Proposition 65 Carcinogens.

Proposition 65

Chemical Status

Cancer: Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Safe Harbor Levels

No Significant Risk Level (NSRL)
0.5 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer: