Melphalan

CAS Number

148-82-3

Synonym

Alanine nitrogen mustard; Alkeran; Alanine nitrogen mustard; CB 3025; Melfalan; Mephalan; NCI-C04853; L-PAM; Phenylalanine mustard; L-phenylalanine mustard; Phenylalanine nitrogen mustard; Sarcoclorin; L-sarcolysin; P-l-sarcolysin; Sarcolysine; L-3-(para-(bis(2-chloroethyl)amino)phenyl)alanine; 4-(bis(2-chloroethyl)amino)-l-phenylalanine; Para-di(2-chloroethyl)aminophenylalanine

Occurrence/Use

Medicine (alkylating agent- multiple myeloma, ovarian cancer)

Melphalan

Cancer Potency Information

Latest Criteria: Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 3.7 E-2
Inhalation Slope Factor (mg/kg-day)-1: 1.3 E+2
Oral Slope Factor (mg/kg-day)-1: 1.3 E+2
Comments/References:

OEHHA 1992. Expedited Cancer Potency Values and Proposed Regulatory Levels for Certain Proposition 65 Carcinogens.

Proposition 65

Chemical Status

Cancer: Currently listed
Reproductive Toxicity : Currently listed

Cancer

Cancer - Listing Mechanism
Labor Code
Listed as causing : Listed as causing: Cancer
Date of Listing:

Reproductive Toxicity

Listed as causing: Developmental Toxicity
Developmental Toxicity
Date of Listing:
Basis for Listing : Formally Required

Safe Harbor Levels

No Significant Risk Level (NSRL)
0.005 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer: