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Ethylene Oxide

CAS Number

75-21-8

Synonym

AI3-26263; Amprolene; Anprolene; Caswell No. 443; Dihydrooxirene; Dimethylene oxide; Epoxyethane; Ethene oxide; Ethox; Fema No. 2433; NCI-C50088; Oxacyclopropane; Oxane; Oxirane; Oxyfume; EPA Pesticide Code: 042301

Occurrence/Use

Agricultural product fumigant, disinfectant (hospital equipment), thermobaric weapons; organic chemical synthesis (ethylene glycol and higher glycols), production of detergents, solvents, plastics, adhesives, antifreeze, pharmaceuticals; component of tobacco smoke

Ethylene Oxide

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 
8.8 E-5
Inhalation Slope Factor (mg/kg-day)-1: 
3.1 E-1
Oral Slope Factor (mg/kg-day)-1: 
3.1 E-1
Comments/References: 

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Air

Chronic REL

Chronic Inhalation REL (μg/m3): 
30
Chronic Target Organs: 
Nervous system
Human Data: 
No
Last Chronic REL Revision: 
2000
Chronic Reference Exposure Levels Comments: 

Proposition 65

Chemical Status

Cancer: 
Currently listed
Reproductive Toxicity: 
Currently listed

Cancer

Listed as causing: 
Cancer
Date of Listing: 
07/01/1987
Basis for Listing: 
Formally Required

Reproductive Toxicity

Listed as causing: 
Developmental Toxicity
Male Reproductive Toxicity
Female Reproductive Toxicity
Developmental Toxicity
Date of Listing: 
08/07/2009
Basis for Listing: 
Formally Required
Male Reproductive Toxicity
Date of Listing: 
08/07/2009
Basis for Listing: 
Formally Required
Female Reproductive Toxicity
Date of Listing: 
02/27/1987
Basis for Listing: 
Formally Required

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
2 µg/day
Reproductive Toxicity
Maximum Allowable Dose Level (MADL) : 
20 µg/day

Comments

Basis for listing ethylene oxide as known to the State to cause developmental toxicity, male reproductive toxicity, and female reproductive toxicity changed from Labor Code to 'Formally Required to Be Labeled or Identified' effective November 22, 2013.

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