Ethylene Oxide
CAS Number
75-21-8Synonym
AI3-26263; Amprolene; Anprolene; Caswell No. 443; Dihydrooxirene; Dimethylene oxide; Epoxyethane; Ethene oxide; Ethox; Fema No. 2433; NCI-C50088; Oxacyclopropane; Oxane; Oxirane; Oxyfume; EPA Pesticide Code: 042301
Occurrence/Use
Agricultural product fumigant, disinfectant (hospital equipment), thermobaric weapons; organic chemical synthesis (ethylene glycol and higher glycols), production of detergents, solvents, plastics, adhesives, antifreeze, pharmaceuticals; component of tobacco smoke
Cancer Potency Information
| Inhalation Unit Risk (μg/cubic meter)-1: | 8.8 E-5 |
|---|---|
| Inhalation Slope Factor (mg/kg-day)-1: | 3.1 E-1 |
| Oral Slope Factor (mg/kg-day)-1: | 3.1 E-1 |
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. |
Air
Chronic REL
| Chronic Inhalation REL (μg/m3): | 30 |
|---|---|
| Chronic Target Organs: | Nervous system |
| Human Data: | No |
| Last Chronic REL Revision: | 2000 |
| Chronic Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3 |
Proposition 65
Chemical Status
| Cancer: | Currently listed |
|---|---|
| Reproductive Toxicity : | Currently listed |
Cancer
Cancer - Listing Mechanism
Formally Required
| Listed as causing : | Listed as causing: Cancer |
|---|---|
| Date of Listing: |
Reproductive Toxicity
Date of Listing
| Listed as causing: | Developmental Toxicity Male Reproductive Toxicity Female Reproductive Toxicity |
|---|---|
| Developmental Toxicity | |
| Date of Listing: | |
| Basis for Listing : | Formally Required |
| Male Reproductive Toxicity | |
| Date of Listing: | |
| Basis for Listing : | Formally Required |
| Female Reproductive Toxicity | |
| Basis for Listing: | Formally Required |
Safe Harbor Levels
No Significant Risk Level (NSRL)
2 µg/day
| Cancer | |
| Reproductive Toxicity | |
| Maximum Allowable Dose Level (MADL) : | 20 µg/day |
|---|
Comments
Basis for listing ethylene oxide as known to the State to cause developmental toxicity, male reproductive toxicity, and female reproductive toxicity changed from Labor Code to 'Formally Required to Be Labeled or Identified' effective November 22, 2013.
Public notices related to this chemical
- Notice of Change to the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead
- Notice to Interested Parties Proposition 65 Listed Chemicals Affected by Hazard Communications Standard Amendments
- Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead
- Chemicals Listed Effective August 7, 2009 as Known to the State of California to Cause Cancer or Reproductive Toxicity
- Chemicals Proposed for Listing by the Labor Code Mechanism (Reproductive and Developmental Toxicants)