Epichlorohydrin
CAS Number
106-89-8Synonym
DL-a-epichlorohydrin; Chloropropylene; 1-Chloro-2,3-Epoxy Propone; (Chloromethyl) Ethylene Oxide; Chloropropylene Oxide; Ech; Glycerol Epichlorohydrin; 1-Chloro-2,3-epoxypropane; gamma-Chloropropylene oxide; chloro-2,3-epoxypropane; (chloromethyl)oxirane; 2-(Chloromethyl)oxirane; chloromethyl; 3-chloro-1,2-epoxypropane; 3-chloro-1,2-propylene oxide; alpha-epichlorohydrin; 1,2-epoxy-3-chloropropane
Occurrence/Use
Production of synthetic materials, including epoxy and phenoxy resins, synthetic glycerol, and elastomers; solvent, fumigant; chemical intermediate
Cancer Potency Information
| Inhalation Unit Risk (μg/cubic meter)-1: | 2.3 E-5 |
|---|---|
| Inhalation Slope Factor (mg/kg-day)-1: | 8.0 E-2 |
| Oral Slope Factor (mg/kg-day)-1: | 8.0 E-2 |
| Comments/References: |
OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. |
Air
Acute RELs
| Acute REL (μg/m3): | 1300 |
|---|---|
| Species: | Human |
| Acute REL Toxicologic Endpoint: | Respiratory and eye irritation |
| Acute REL Target Organs: | Respiratory system, eyes |
| Severity: | Mild |
| Last Acute REL Revision: | 1999 |
| Acute Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D2. |
Chronic REL
| Chronic Inhalation REL (μg/m3): | 3 |
|---|---|
| Chronic Target Organs: | Respiratory system, eyes |
| Human Data: | No |
| Last Chronic REL Revision: | 2000 |
| Chronic Reference Exposure Levels Comments: |
OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3
|
Proposition 65
Chemical Status
| Cancer: | Currently listed |
|---|---|
| Reproductive Toxicity : | Currently listed |
Cancer
Cancer - Listing Mechanism
State's Qualified Experts
| Listed as causing : | Listed as causing: Cancer |
|---|---|
| Date of Listing: |
Reproductive Toxicity
| Listed as causing: | Male Reproductive Toxicity |
|---|---|
| Male Reproductive Toxicity | |
| Date of Listing: | |
| Basis for Listing : | Authoritative Bodies-US Environmental Protection Agency |
Safe Harbor Levels
No Significant Risk Level (NSRL)
9 µg/day
| Cancer |