Chlorambucil

CAS Number

305-03-3

Synonym

4-(p[bis(2-Chloroethyl)amino]phenyl)butyricacid; Ambochlorin; CB 1348; Chloraminophen; Chloraminophene; Chlorambucil; Chlorobutine; Eclorin; Leukeran; Linfolizin; Linfolysin; NSC 3088

Occurrence/Use

Medicine (leukemia treatment), insect sterilant

Cancer Potency Information

Latest Criteria:	Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1:	0.13
Inhalation Slope Factor (mg/kg-day)-1:	440
Oral Slope Factor (mg/kg-day)-1:	0.0023
Comments/References:	OEHHA 1992. Expedited Cancer Potency

Proposition 65

Chemical Status

Cancer:	Currently listed
Reproductive Toxicity :	Currently listed

Cancer

Cancer - Listing Mechanism

Labor Code

Listed as causing :	Listed as causing: Cancer
Date of Listing:	02/27/1987

Reproductive Toxicity

Listed as causing:	Developmental Toxicity
Developmental Toxicity
Date of Listing:	01/01/1989
Basis for Listing :	State's Qualified Experts

Safe Harbor Levels

No Significant Risk Level (NSRL)

0.002 µg/day

Cancer
Last NSRL/MADL Revision:	1992

Documents, Presentations, and Publications

Cancer:	Expedited Cancer Potency Values April 1, 1992