Bisphenol-A
CAS Number
80-05-7Synonym
4,4'-(propane-2,2-diyl)diphenol, BPA, p,p'-isopropylidenebisphenol,
2,2-bis(4-hydroxyphenyl)propane
Occurrence/Use
Used to make certain plastics and epoxy resins. BPA-based plastic is made into a variety of common consumer goods, such as water bottles, sports equipment, CDs, and DVDs. Epoxy resins containing BPA are used as coatings on the inside of many food and beverage cans and in making thermal paper such as that used in sales receipts.
Proposition 65
MADL w/ File
Chemical Status
| Cancer: | Considered, but not listed |
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| Reproductive Toxicity : | Currently listed |
Reproductive Toxicity
| Listed as causing: | Developmental Toxicity Female Reproductive Toxicity | Developmental Toxicity |
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| Date of Listing: | |
| Basis for Listing : | Authoritative Bodies-National Toxicology Program-Center for the Evaluation of Risks to Human Reproduction | Female Reproductive Toxicity |
| Basis for Listing: | State's Qualified Experts |
Safe Harbor Levels
| Reproductive Toxicity | |
| Maximum Allowable Dose Level (MADL) : | 3µg/day (dermal exposure from solid materials) |
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Documents, Presentations, and Publications
| Cancer: |
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| Reproductive Toxicity: |
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Comments
Public notices related to this chemical
- Request for Relevant Information on the Developmental and Reproductive Toxicity of: Bisphenol-A, Chlorpyrifos, Chromium, DDE, Sulfur dioxide
- Hazard Identification Materials for Bisphenol A (developmental and reproductive toxicity)
- Request for Information on a Chemical Being Considered for Listing by the Authoritative Bodies Mechanism: Bisphenol-A
- Proposed Amendment to Section 25805 Specific Regulatory Levels: Chemicals Causing Reproductive Toxicity Bisphenol-A
- Notice of Intent to List: Bisphenol-A
- Bisphenol-A (BPA) Listed as Known to the State of California to Cause Reproductive Toxicity
- Bisphenol-A (BPA) Delisted as Known to the State of California to Cause Reproductive Toxicity
- Hazard Identification Materials for Consideration of the Female Reproductive Toxicity of Bisphenol-A
- Bisphenol-A Listed as Known to the State of California to Cause Reproductive Toxicity
- Notice of Proposed Rulemaking Title 27, California Code of Regulations Maximum Allowable Dose Level for Bisphenol A (Dermal Exposure from Solid Materials)
- Amendment to Section 25805, Maximum Allowable Dose Level - Bisphenol A (Dermal Exposure from Solid Materials)
BPA was originally listed as causing reproductive toxicity on April 11, 2013 for the developmental toxicity endpoint, but subsequently delisted pending resolution of a court case. BPA was re-listed as causing reproductive toxicity on May 11, 2015 for the female reproductive toxicity endpoint. In 2020 the court case regarding the developmental toxicity endpoint was resolved and OEHHA reinstated the developmental toxicity endpoint on December 18, 2020.
Meetings
Overview of the 2022 Meeting of the Carcinogen Identification Committee (CIC)