4,4-Methylenedianiline

CAS Number

101-77-9

Synonym

Curithane; DAPM; DDM; Diaminodiphenylmethane; 4,4-diphenylmethanediamine; Epicure DDM; Methylenebis(aniline); Methylenedianiline; Tonox; MDA; 4,4'-Diaminodiphenylmethane

Occurrence/Use

Chemical intermediate in production of polyurethane foams, epoxy resins and adhesives, high-performance polymers, azo dyes, and elastomeric fibers; corrosion inhibitor, antioxidant

4,4-Methylenedianiline

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 4.6 E-4
Inhalation Slope Factor (mg/kg-day)-1: 1.6 E+0
Oral Slope Factor (mg/kg-day)-1: 1.6 E+0
Comments/References:

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Air

Chronic REL

Chronic Inhalation REL (μg/m3): 20
Chronic Target Organs: Eyes, alimentary system (liver)
Human Data: No
Last Chronic REL Revision: 2001
Chronic Reference Exposure Levels Comments:

OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3

 

Proposition 65

Chemical Status

Cancer: Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Safe Harbor Levels

No Significant Risk Level (NSRL)
0.4 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer: