2,5-Hexanedione
CAS Number
110-13-4Synonym
1,2-Diacetylethane
Acetonyl Acetone
Diacetonyl
2,5-Dioxohexane
2,5-Diketohexane
Occurrence/Use
Used as a starting reagent in the synthesis of trans-2,5-dimethylpyrrolidine and other pyrroles. It is also described as a “reagent used for the protection of amino groups in amino sugars and nucleosides; for the synthesis of five-membered heterocycles, in particular 2,5-dimethyl aminopyrroles, indane-type and benzannulated systems”.
Date Added
Proposition 65
Chemical Status
| Reproductive Toxicity : | Currently listed |
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Reproductive Toxicity
| Listed as causing: | Male Reproductive Toxicity | Male Reproductive Toxicity |
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| Date of Listing: | |
| Basis for Listing : | State's Qualified Experts |
Documents, Presentations, and Publications
| Reproductive Toxicity: |
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Public notices related to this chemical
- Chemical Listed Effective December 4, 2015 as Known to the State of California to Cause Reproductive Toxicity: 2,5-Hexanedione and Addition of a Reproductive Toxicity Endpoint (Developmental) for Methyl-N-Butyl Ketone
- Reconsideration of Listing of Methyl-n-butyl Ketone and Consideration of Listing of 2,5-Hexanedione