1,3-Butadiene
CAS Number
106-99-0Synonym
Vinylethylene; Erthrene; Bivinyl; Divinyl
Occurrence/Use
Polymer component in production of synthetic rubber, plastic, and fuel; chemical intermediate (nylon); component of tobacco smoke
Cancer Potency Information
Inhalation Unit Risk (μg/cubic meter)-1: | 1.7 E-4 |
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Inhalation Slope Factor (mg/kg-day)-1: | 6.0 E-1 |
Oral Slope Factor (mg/kg-day)-1: | 6.0 E-1 |
Comments/References: |
OEHHA 2009. Air Toxics Hot Spot Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. |
Air
Acute RELs
Acute REL (μg/m3): | 660 |
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Species: | Mouse |
Acute REL Toxicologic Endpoint: | Development (low male fetal weight) |
Acute REL Target Organs: | Development |
Severity: | Severe |
Last Acute REL Revision: | 2013 |
Acute Reference Exposure Levels Comments: |
8-Hour RELs
8-Hour Inhalation REL (μg/m3): | 9 |
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Last 8-Hour REL Revision: | 2013 |
8-Hour Reference Exposure Levels Comments: |
OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. |
Chronic REL
Chronic Inhalation REL (μg/m3): | 2 |
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Chronic Target Organs: | Reproductive system |
Human Data: | No |
Last Chronic REL Revision: | 2013 |
Chronic Reference Exposure Levels Comments: |
Proposition 65
Chemical Status
Cancer: | Currently listed |
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Reproductive Toxicity : | Currently listed |
Cancer
Listed as causing : | Listed as causing: Cancer |
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Date of Listing: |
Reproductive Toxicity
Listed as causing: | Developmental Toxicity Male Reproductive Toxicity Female Reproductive Toxicity | Developmental Toxicity |
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Date of Listing: | |
Basis for Listing : | Authoritative Bodies-National Institute for Occupational Safety and Health Authoritative Bodies-US Environmental Protection Agency | Male Reproductive Toxicity |
Date of Listing: | |
Basis for Listing : | Authoritative Bodies-National Institute for Occupational Safety and Health Authoritative Bodies-US Environmental Protection Agency | Female Reproductive Toxicity |
Basis for Listing: | Authoritative Bodies-National Institute for Occupational Safety and Health Authoritative Bodies-US Environmental Protection Agency |
Safe Harbor Levels
Cancer |
Documents, Presentations, and Publications
Reproductive Toxicity: |
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