Comment Period - Notice of Intent to List Nine Chemicals

In a notice dated September 27, 1996, OEHHA announced that these chemicals were under consideration for listing based on a review of information indicating that the chemicals may meet the criteria set forth in 22 CCR, Section 12306 or Section 12902. OEHHA solicited comments and information relevant to the evaluation of these chemicals in the context of the regulatory criteria for administrative listing under Proposition 65. The public comment period commenced on September 27, 1996, and closed on, November 26, 1996. A public forum was held on October 29, 1996 to provide an opportunity for oral comments. OEHHA has reviewed the information received during the public comment period, and has determined that the nine chemicals identified below meet the criteria for listing under either 22 CCR, Section 12306, or Section 12902.

Anyone objecting to the listing of the chemicals identified under Section A below as carcinogens on the basis that there is no substantial evidence that the criteria of sufficiency of evidence of carcinogenicity identified in 22CCR, Section 12306 have been satisfied, or to the listing of the carcinogens and reproductive toxicants identified in Section B below on the basis that the criteria in 22 CCR, Section 12902 have not been met, should provide written comments, along with supporting documentation, by mail or by fax to:

Proposition 65 Office
Office of Environmental Health Hazard Assessment
P.O. Box 4010, MS-19B
Sacramento, California 95812-4010
Fax: (916) 323-2265

Street Address: 1001 I Street
Sacramento, California 95814

Comments may also be hand-delivered to the Proposition 65 Office of the Office of Environmental Health Hazard Assessment, 1001 I Street, Sacramento, California.

In order to be considered, comments must be postmarked (if sent by mail) or received at OEHHA (if hand-delivered or sent by fax) by, March 10, 1997.

A. The following agents have been determined by OEHHA to meet the criteria set forth in 22 CCR, Section 12306 for listing as carcinogens under the authoritative bodies mechanism:

Chemical CAS No. Reference
Nitromethane 75-52-5 NTP (1995a; 1995c)
Tetrafluoroethylene 116-14-3 NTP (1995b; 1995c)
Vinyl Fluoride 75-02-5 IARC (1995)

B. The following agents have been determined by OEHHA to meet the criteria set forth in 22 CCR, Section 12902 for listing based on a formal requirement for labeling or identification as causing cancer or reproductive toxicity:

Carcinogens:

Chemical CAS No. Reference
Spironolactone 52-01-7 FDA, 1990
Stanozolol 10418-03-8 FDA, 1992

Reproductive toxicants:

Chemical CAS No. Reference Type of
Reproductive Toxicity
Clarithromycin 81103-11-9 FDA, 1995a developmental
Dihydroergotamine mesylate 6190-39-2 FDA, 1994 developmental
Hydroxyurea 127-07-1 FDA, 1971 developmental
Oxymetholone 434-07-1 FDA, 1993 developmental