Comment Period - Notice of Intent to List Nine Chemicals
In a notice dated September 27, 1996, OEHHA announced that these chemicals were under consideration for listing based on a review of information indicating that the chemicals may meet the criteria set forth in 22 CCR, Section 12306 or Section 12902. OEHHA solicited comments and information relevant to the evaluation of these chemicals in the context of the regulatory criteria for administrative listing under Proposition 65. The public comment period commenced on September 27, 1996, and closed on, November 26, 1996. A public forum was held on October 29, 1996 to provide an opportunity for oral comments. OEHHA has reviewed the information received during the public comment period, and has determined that the nine chemicals identified below meet the criteria for listing under either 22 CCR, Section 12306, or Section 12902.
Anyone objecting to the listing of the chemicals identified under Section A below as carcinogens on the basis that there is no substantial evidence that the criteria of sufficiency of evidence of carcinogenicity identified in 22CCR, Section 12306 have been satisfied, or to the listing of the carcinogens and reproductive toxicants identified in Section B below on the basis that the criteria in 22 CCR, Section 12902 have not been met, should provide written comments, along with supporting documentation, by mail or by fax to:
Proposition 65 Office
Office of Environmental Health Hazard Assessment
P.O. Box 4010, MS-19B
Sacramento, California 95812-4010
Fax: (916) 323-2265
Street Address: 1001 I Street
Sacramento, California 95814
Comments may also be hand-delivered to the Proposition 65 Office of the Office of Environmental Health Hazard Assessment, 1001 I Street, Sacramento, California.
In order to be considered, comments must be postmarked (if sent by mail) or received at OEHHA (if hand-delivered or sent by fax) by, March 10, 1997.
A. The following agents have been determined by OEHHA to meet the criteria set forth in 22 CCR, Section 12306 for listing as carcinogens under the authoritative bodies mechanism:
Chemical | CAS No. | Reference |
---|---|---|
Nitromethane | 75-52-5 | NTP (1995a; 1995c) |
Tetrafluoroethylene | 116-14-3 | NTP (1995b; 1995c) |
Vinyl Fluoride | 75-02-5 | IARC (1995) |
B. The following agents have been determined by OEHHA to meet the criteria set forth in 22 CCR, Section 12902 for listing based on a formal requirement for labeling or identification as causing cancer or reproductive toxicity:
Carcinogens:
Chemical | CAS No. | Reference |
---|---|---|
Spironolactone | 52-01-7 | FDA, 1990 |
Stanozolol | 10418-03-8 | FDA, 1992 |
Reproductive toxicants:
Chemical | CAS No. | Reference | Type of Reproductive Toxicity |
---|---|---|---|
Clarithromycin | 81103-11-9 | FDA, 1995a | developmental |
Dihydroergotamine mesylate | 6190-39-2 | FDA, 1994 | developmental |
Hydroxyurea | 127-07-1 | FDA, 1971 | developmental |
Oxymetholone | 434-07-1 | FDA, 1993 | developmental |