Comment Period - Notice of Intent to List Chemicals by the Labor Code Mechanism: Chloral, chloral hydrate, 1,1,1,2-tetrachloroethane, and trichloroacetic acid
OEHHA’s determination: Chloral, chloral hydrate, 1,1,1,2-tetrachloroethane, and trichloroacetic acid each meet the requirements for listing as known to the state to cause cancer for purposes of Proposition 65.
IARC has published on its website a list entitled “Agents classified by the IARC Monographs, Volume 1-106" (link is external) (IARC, 2012). IARC concludes that chloral and chloral hydrate are each classified in Group 2A (the agent is “probably carcinogenic to humans”) and1,1,1,2-tetrachloroethane andtrichloroacetic acidare each classified in Group 2B (the agent is “possibly carcinogenic to humans”). IARC concludes that there is “sufficient evidence of carcinogenicity in experimental animals” for chloral, chloral hydrate, 1,1,1,2-tetrachloroethane andtrichloroacetic acid (Guha et al., 2012 (link is external)). Therefore, these substances meet the requirements of both Labor Code sections 6382(b)(1) and (d).
Opportunity for comment: OEHHA is providing this opportunity to comment as to whether the chemicals identified above meet the requirements for listing as causing cancer specified in Health and Safety Code section 25249.8(a). Because these are ministerial listings, comments should be limited to whether IARC has identified the specific chemical or substance as a known or potential human or animal carcinogen. Under this listing mechanism, OEHHA cannot consider scientific arguments concerning the weight or quality of the evidence considered by IARC when it identified these chemicals and will not respond to such comments if they are submitted.
OEHHA must receive comments by 5:00 p.m. on Monday, August 26, 2013. We encourage you to submit comments in electronic form, rather than in paper form. Comments transmitted by e-mail should be addressed to P65Public.Comments@oehha.ca.gov, and should include “NOIL” and the chemical name in the subject line. Comments submitted in paper form may be mailed, faxed, or delivered in person to the address below. A public workshop will be held only upon request. Such request must be made in writing within 10 days from the publication of this notice to the Proposition 65 Office of OEHHA via email at sam.delson@oehha.ca.gov or to the attention of the Proposition 65 Office at the address listed below:
Mailing Address: Sam Delson
Office of Environmental Health Hazard Assessment
P.O. Box 4010, MS-19B
Sacramento, California 95812-4010
Fax: (916) 323-2265
Street Address: 1001 I Street
Sacramento, California 95814
Any public comments received will be posted after the close of the comment period. If you have any questions, please contact Sam Delson at sam.delson@oehha.ca.gov or at (916) 445-6900.