Request for Relevant Information on the Carcinogenicity of Bisphenol A (BPA)

Request for Information

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) has selected bisphenol A (BPA) for the Carcinogen Identification Committee (CIC)’s review for possible listing under Proposition 65 and is soliciting information relevant to the assessment of its carcinogenicity. BPA was selected from chemicals prioritized^[1] by the CIC in 2020.

Relevant information on BPA includes but is not limited to: 

• Cancer bioassays
• Cancer epidemiological studies
• Studies related to cancer mechanisms and the key characteristics of carcinogens
• Other pertinent studies on:
  • Pharmacokinetics
  • Effects on biochemical and physiological processes, including findings in humans

Interested parties wishing to provide such information should submit it in accordance with the instructions given below.

The publication of this notice marks the start of a 45-day data call-in period, ending on Monday, March 14, 2022. The information received during this period will be reviewed and considered by OEHHA as it prepares the cancer hazard identification materials on BPA.

Background

OEHHA is the lead agency for the implementation of Proposition 65^[2]. The CIC of OEHHA’s Science Advisory Board serves as the state’s qualified experts and renders an opinion about whether a chemical has been clearly shown to cause cancer^[3]. Chemicals identified as carcinogens by the CIC are added to the Proposition 65 list. 

Hazard identification materials will be made available to the public for comment prior to the CIC’s consideration of the chemical for possible listing. The availability of hazard identification materials will be announced in the California Regulatory Notice Register and on OEHHA’s website.

Comment Submittal

OEHHA strongly recommends that relevant information responsive to this request be submitted electronically through our website at https://oehha.ca.gov/comments, rather than in paper form. Comments submitted in paper form can be mailed or delivered in person to the address below.

All non-electronic submissions should be directed to:

Tyler Saechao
Office of Environmental Health Hazard Assessment
1001 I Street
P.O. Box 4010, MS-12B
Sacramento, California 95812-4010
Telephone: 916-445-6900